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Korean Journal of Bone Metabolism 2010;17(1):31-38.
Study about Relationships between Young Age s Body Mass Index (BMI) and Postmenopausal BMI for Bone Mineral Density (BMD) in Postmenopausal Osteoporosis Patients
폐경 후 골다공증 환자에서 골밀도에 대한 젊은 시절 및 폐경 후 체질량지수와의 관련성에 대한 연구
순천향대학교 의과대학 내분비내과
Among the various kinds of osteoporosis s risk factor, body weight (BW) is one of the most important factor for osteoporotic fracture. But young age s BW or body mass index (BMI) is not studied for the relationship with BMD in postmenopausal patients. So author investigated the relationships between young age s BMI and postmenopausal BMI for BMD in postmenopausal Korean women.
From Jan. 2005 to Sep. 2009, total 109 postmenopausal women who visited endocrinology department of Soonchunhyang University Hospital were enrolled. All the subjects were checked current and young age s BW, BMI and BMD. Patients were devided by 2 groups, one was osteoporosis group (OS, n = 38) and the other was normal and osteopenia group (OP, n = 37).
Total 75 subjects who's mean age was 61.07 years and BMI was 23.5 kg/m2 were included. BMI at young age was 20.29 kg/m2 in osteoprosis (OS) group and 20.30 kg/m2 in normal and osteopenia (OP) group which showed no statistical difference. BW after postmenopausal period showed significant correlations with lumbar spine (r = 0.292, P = 0.011), femur neck (r = 0.283, P = 0.014), total hip (r = 0.271, P = 0.019). But BW at young age showed significant correlations only with lumbar spine (r = 0.265, P = 0.021). BW change from young age to postmenopausal period showed significant difference (P = 0.03) between OS group (5.23 ± 7.21 kg) and normal and OP group (9.81 ± 10.31 kg).
Young age s BW was only correlated with lumbar spine BMD and young age s BMI were not correlated with BMD. BW changes are bigger in normal and OP group than OS group which means that weight gain after peak bone mass formation to menopausal period is more important than young age's BW for prevention of osteoprosis. [Korean Journal of Bone Metabolism, 17(1): 31-38, 2010]
Key Words: Osteoporosis, Risk factors, Body mass index, Bone mineral density, Body weight


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