Objective
s: To evaluate the prevalence of osteoporosis in the Alzheimer s disease patients.
Methods
One hundred and twenty eight patients with Alzheimer s disease were included in this study. The patients
are diagnosed with Alzheimer s disease using Korean-Mini Mental Status Examination (K-MMSE) and checked bone
mineral density using single-energy (SE) quantitative computed tomography (QCT) in 2010. To define abnormality
in terms of QCT of the spine, a bone mineral density (BMD) spine below 80 mg/cm3 is indicative of osteoporosis and
BMD between 80 and 120 mg/cm3 is indicative osteopenia.
Results
The prevalence of osteoporosis in the control group is 29.73%. The prevalence of osteoporosis in the
Alzheimer s disease patients is 96.87%. The prevalence of osteopenia in the Alzheimer's disease patients is 3.12%.
The prevalence of severe osteoporosis fracture in the Alzheimer s disease patients is 32.03%.
Conclusion
The prevalence of osteoporosis in Alzheimer's disease patients is higher than in the control group.
