Korean J Bone Metab > Volume 18(2); 2011 > Article
Korean Journal of Bone Metabolism 2011;18(2):125-130.
The Survey of Prevalence of Osteoporosis in Alzheimer s Disease Patients
알츠하이머병 환자에서의 골밀도 확인
기엽,안기용,윤태현,임채준,신우진
서남대학교 남광병원 정형외과학교실1, 남평 미래병원 정형외과2
Abstract
Objective
s: To evaluate the prevalence of osteoporosis in the Alzheimer s disease patients.
Methods
One hundred and twenty eight patients with Alzheimer s disease were included in this study. The patients are diagnosed with Alzheimer s disease using Korean-Mini Mental Status Examination (K-MMSE) and checked bone mineral density using single-energy (SE) quantitative computed tomography (QCT) in 2010. To define abnormality in terms of QCT of the spine, a bone mineral density (BMD) spine below 80 mg/cm3 is indicative of osteoporosis and BMD between 80 and 120 mg/cm3 is indicative osteopenia.
Results
The prevalence of osteoporosis in the control group is 29.73%. The prevalence of osteoporosis in the Alzheimer s disease patients is 96.87%. The prevalence of osteopenia in the Alzheimer's disease patients is 3.12%. The prevalence of severe osteoporosis fracture in the Alzheimer s disease patients is 32.03%.
Conclusion
The prevalence of osteoporosis in Alzheimer's disease patients is higher than in the control group.
Key Words: Alzheimer disease, Osteoporosis, Prevalence


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