Bone Regeneration from Adipose Stem Cells |
지방줄기세포를 이용한 골재생 |
임군일,이재선 |
동국대학교 의과대학 |
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Abstract |
Reconstruction of large bone defect poses a great challenge to an orthopedic surgeon. Recent advancement in stem
cell research ushered the treatment of bone defect with tissue-engineered bone into near-possibility. While adipose
stem cells (ASCs) are the most available cell sources for tissue regeneration, their low osteogenic potential is a
disadvantage. Several strategies have been developed to enhance the osteogenic differentiation of ASCs. In this review,
we summarized literatures and our experience on the technology to promote osteogenesis from ASCs. |
Key Words:
Adipose tissue, Bone regeneration, Mesenchymal stem cell, Osteogenesis |
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