| Low Energy Femur Shaft and Subtrochanteric Fracture with Biphosphonate Therapy |
| Biphosphonate 사용력이 있는 환자에서 저에너지 손상으로
발생한 대퇴 간부 및 전자하 골절 |
| 김지완1,김정재,이희상,주석규2,오형근2,장재석 |
| 울산대학교 의과대학 서울아산병원 정형외과학교실, 인제대학교 의과대학 해운대 백병원 정형외과학교실1,
인제대학교 의과대학 일산 백병원 정형외과교실2 |
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| Abstract |
Purpose
The purpose of this study is to investigate the rate of bisphosphonate use among low energy femur shaft/
subtrochanteric fractures and to analyze the differences in clinical features between bisphosphonate treated group and
the control group.
Methods
We performed a retrospective study of postmenopausal women with low energy femoral shaft/subtrochanteric
fractures from August 2002 to May 2009. Six subtrochanteric and 44 femoral shaft fractures were identified. The
patients were divided into two groups: group A, patients who had a history of bisphosphonate treatment; group B, those
who served as control. Age, union time, BMD and x-ray findings were compared between the two groups.
Results
Fifteen (30%) were being treated with bisphosphonate and the average duration of bisphophonate treatment
was 39.5 months. Eight patients (53.3%) presented with a prodromal symptom, thigh pain and four patients (26.7%)
showed bilateral lesions. The average age of group A and B was 71.0 and 70.6 years (P = 0.780), and the average union
time of group A and B was 4.1 and 4.7 months (P = 0.475), respectively. The characteristic x-ray pattern was observed
in 15 cases (100%) among group A, and 2 cases(5.7%) among group B (P < 0.001). The patients with BMD below
T-score -2.5 were 13 cases (86.7%) in group A and 22 cases (62.9%) in group B (P = 0.765).
Conclusion
The rate of bisphosphonate use was 30% in the low energy femoral subtrochanteric/shaft fracture cases in
the postmenopausal patients. The findings of this study suggest that medical practitioners should be careful with the
osteoporosis patients who use prolonged bisphosphonate with thigh pain.
[Korean Journal of Bone Metabolism, 17(1): 19-23, 2010] |
| Key Words:
Insufficiency fracture, Biphosphonate |
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