Korean J Bone Metab > Volume 16(2); 2009 > Article
Korean Journal of Bone Metabolism 2009;16(2):71-77.
Comparison of the Bone Mineral Density between Quantitative Computed Tomography and Dual Energy X-ray Absorptiometry in the Proximal Femur
근위부 대퇴골에서 정량적 컴퓨터 단층 촬영으로 측정한 골밀도와 이중 에너지 방사선 흡수 계측법으로 측정한 골밀도의 비교
김지완,차영찬,신명진1,장재석
울산대학교 의과대학 서울아산병원 정형외과학교실, 영상의학과교실1
Abstract
Objective
The purpose of the present study is to compare the bone mineral density (BMD) evaluated by dual energy x-ray absorptiometry(DXA) and quantitative computed tomography (QCT).
Methods
From December 2008 to April 2009, 32 patients with hip fracture or hip disease were enrolled in our study. BMD of the contralateral, normal side of the proximal femur was measured by DXA and QCT. The differences of BMD in the femoral neck, trochanter, total proximal femur and ward area in the two methods were analyzed using the Wilcoxon signed rank test. The relationship of each BMD in the two methods was evaluated using the Spearman correlation coefficient.
Results
BMD of the femoral neck was 0.644 ± 0.132 g/cm2 by DXA and 0.516 ± 0.116 g/cm2 by QCT. Trochanter BMD was 0.526 ± 0.141 g/cm2 by DXA and 0.407 ± 0.125 g/cm2 by QCT. Total proximal femur BMD was measured as 0.660 ± 0.139 g/cm2 and 0.547 ± 0.129 g/cm2, while the BMD in the Ward area was 0.437 ± 0.131 g/cm2 and 0.299 ± 0.167g/cm2. respectively according to DXA and QCT. The Wilcoxon signed rank test confirmed the differences of BMD between DXA and QCT in all areas (P < 0.001). The Spearman correlation coefficient was 0.699, 0.967, 0.951, and 0.460, respectively, at the femoral neck, trochanter, total proximal femur, and Ward area, and these correlations were statistically significant (P < 0.001).
Conclusion
The average BMD measured by QCT was lower than that by DXA. The BMD in the two methods showed positive correlation. Therefore we conclude that BMD using QCT measured lower than BMD using DXA. [Korean Journal of Bone Metabolism, 16(2): 71-77, 2009]
Key Words: Osteoporosis, Bone mineral density, Quantitative computed tomography, Dual energy x-ray absorptiometry


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