Korean J Bone Metab > Volume 15(1); 2008 > Article
Korean Journal of Bone Metabolism 2008;15(1):85-89.
A Case of Parathyroid Carcinoma Mimicking Bone Tumor
골종양으로 의심된 부갑상선암 1예
김은아,이정진,하기철,정영국,유성수,김소헌,홍성빈,남문석,김용성,김세중1
인하대학교 의과대학 내과, 외과1
Abstract
Background
Most of primary hyperparathyroidism result from parathyroid adenoma, parathyroid carcinoma is rare, comprising only 0.1% to 5% of all patients with primary hyperparathyroidism. It present with severe hypercalcemia, bone disease, palpable neck mass, and renal involvement. Case: A 37-year-old woman was admitted to the hospital due to pain on the left elbow. MRI of elbow showed multi-septated mass with heterogenous T2 signal intensity. The excisional biopsy of ulnar showed increased number of osteoclast. Then, she was transferred to endocrinology department. Elevated serum calcium and parathyroid hormone (PTH) concentration allowed the diagnosis of hyperparathyroidism. Postoperative histological diagnosis was parathyroid carcinoma with focal invasion to thyroid parenchyma. After operation, the patients was treated with vitamin D and calcium because of hungry bone syndrome. The intact PTH level decreased and calcium level return to normal range.
Conclusion
We reported a rare case of a parathyroid carcinoma mimics bone tumor with mild increased serum calcium level.
Key Words: Parathyroid, Carcinoma


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