Journal of Bone Metabolism

"Kyung-Hag Lee"

Original Articles

Patient Perception on Osteoporosis in Korean Female Patients with Osteoporosis: Kyung-Hag Lee, Guhyun Lee, Taehyun Lee, Dong-Won Byun, Yong-Chan Ha; J Bone Metab 2024;31(1):63-74.
Published online February 29, 2024; DOI: https://doi.org/10.11005/jbm.2024.31.1.63

Background
Patient perception is a key element in improving compliance with medications for osteoporosis. This study evaluated the awareness, perception, sources of information, and knowledge of osteoporosis among Korean women with osteoporosis.
Methods
A questionnaire survey was conducted from July 22, 2021 to 13 August 2021. Patients who were followed up in endocrinology (Endo), orthopedic surgery (OS), and gynecology (GY) were recruited (N=40, 40, and 20 in each group). Patients were allocated according to their age, as follows: 15, 15, and 10 patients in their 60s, 70s, and 80s for Endo and OS, and 10 and 10 patients in their 60s and 70s for GY. The questionnaire was composed of the following topics: patient journey to the hospital, drug-related issues, communication with medical doctors, patient knowledge, and sources of information about osteoporosis.
Results
The results of medical check-ups were the most common reason for patient visits to the hospital for an initial diagnosis of osteoporosis (61%). A knowledge gap regarding mortality, refracture, and drug-induced osteoporosis was observed. Doctors were the most preferred and trustful source of information, while health-related TV shows were the second most common source of information. Patients with OS reported lower perceived severity and higher drug discontinuation, along with a higher proportion of fractures, as the initial reasons for hospital visits for osteoporosis.
Conclusions
Variations in perceptions according to the issue and group were identified. These should be considered during patient consultations to improve compliance with osteoporosis treatment.

Citations

Citations to this article as recorded by

1. Living with osteoporosis: a qualitative descriptive study
Mara Tormen, Chiara Tedesco, Vicente Bernalte-Martì, Angela Cuoco, Anna Maria Carratoni, Gianluca Pucciarelli, Ercole Vellone, Maddalena De Maria, Emanuela Basilici Zannetti, Noemi Cittadini, Annalisa Pennini, Umberto Tarantino, Rosaria Alvaro
Archives of Osteoporosis.2025;[Epub] CrossRef

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Seasonal Variations and Common Places of Hip Fractures in Elderly Patients: Nine Year Consecutive Survey: Kyung-A Choi, Yong-Chan Ha, Kyung-Hag Lee; J Bone Metab 2023;30(1):103-114.
Published online February 28, 2023; DOI: https://doi.org/10.11005/jbm.2023.30.1.103

Background
Fall prevention is important for reducing hip fractures. The aim of this study was to determine the relationship between variables related to hip fractures according to sex and season.
Methods
This study included patients admitted for fragility hip fractures between 2012 and 2021. Patients were interviewed by a junior resident before discharge. Data on sex, age, diagnosis, osteoporosis treatment, direction, voiding problems, ambulatory function, seasons, weather, time of day, place, location, floor condition, activity during fall, and perceived reason for fall were collected and analyzed.
Results
A total of 1,118 patients were included (279 males and 839 females). In both sexes, indoor falls were prevalent throughout all seasons, but males showed a higher proportion of outdoor falls, especially in winter during cloudy or snowy weather. Rooms and walking were the most common locations and activities during falls. The poor ambulatory function was associated with a higher prevalence of indoor falls. Osteoporosis treatment rates were low and did not differ according to Koval stage. Winter was associated with higher osteoporosis non-treatment group. Urgency/incontinence in female patients caused a higher proportion of falls during the evening time.
Conclusions
Strategies for indoor fall prevention and vigilant osteoporosis diagnosis and treatment are important for all seasons, especially for frail elderly patients. Outdoor fall prevention emphasized for male patients, and education around nighttime falls should be provided for female patients with voiding dysfunction.

Citations

Citations to this article as recorded by

1. Causes of Reoperations After Primary Total Hip Arthroplasty: A Retrospective Cohort Study Over 20 Years
Ki-Tae Park, Dong-Hoon Lee, Joon-Hwan An, Jong-Hwa Won, Kyung-Hoi Koo, Jung-Wee Park, Young-Kyun Lee
The Journal of Arthroplasty.2025; 40(9): 2338. CrossRef
2. Relationship Between Sural Nerve Function, Physical Function, and the Ability to Perform Activities of Daily Living in Hospitalized Elderly Patients With Proximal Femoral Fractures: A Prospective Observational Study
Eisuke Takeshima, Akira Kimura
Cureus.2025;[Epub] CrossRef
3. Weather and hip fractures: A nine-year study across England and Wales
Louis J Koizia, Kjeld Jensen, David Yearling, Gav Barang, Benjamin HL Harris, Michael B Fertleman
Injury.2025; 56(12): 112856. CrossRef
4. Indoor falls-related hip and femur fractures decreased during the social distancing period of COVID-19 in South korea: a single-center retrospective cohort study using propensity score matching
Kwan Kyu Park, Byung Woo Cho, Hyuck Min Kwon, Woo-Suk Lee, Kyoung-Tak Kang, Jun Young Park
Aging Clinical and Experimental Research.2025;[Epub] CrossRef

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Prevalence, Clinical Implication, and Cause of Spine Hip Discordance in Elderly Patients with Fragility Hip Fracture: Kyung-Hag Lee, Jung-Wee Park, Sujin Kim, Guen Young Lee, Sung Bin Park, Du-Bin Yang, Yong-Chan Ha; J Bone Metab 2022;29(1):51-57.
Published online February 28, 2022; DOI: https://doi.org/10.11005/jbm.2022.29.1.51

Background
Spine-hip discordance (SHD) increases fracture risk. However, its prevalence and clinical implications have not been investigated in patients with hip fractures. This study determined the prevalence and association of SHD with mortality and investigated the cause of SHD in patients with hip fractures.
Methods
This study included patients admitted for fragility hip fractures between 2011 and 2020. All patients underwent dual energy X-ray absorptiometry and anteroposterior and lateral views of the lumbosacral spine during admission. Data on demographics, diagnosis, American Society of Anesthesiologists score, and mortality were collected. A T-score difference of more than 1.5 between L1-4 and the femur neck was considered discordant, and 3 groups (lumbar low [LL] discordance, no discordance [ND], and femur neck low [FL] discordance) were compared. In the discordance group, lumbar radiographs were reviewed to determine the cause of discordance.
Results
Among 1,220 eligible patients, 130 were excluded due to patient refusal or bilateral hip implantation; therefore, this study included 1,090 patients (271 male and 819 female). The prevalence of LL, ND, and FL was 4.4%, 66.4% and 29.2% in men and 3.9%, 76.1%, and 20.0% women. Mortality was not associated with discordance. The most common causes of discordance were physiological in the LL group and pathological in the FL group for both sexes.
Conclusions
Patients with hip fractures showed lower rates of ND and higher rates of FL compared to the general population. True discordance should be carefully judged for pathological and artifact reasons. The clinical implications of SHD require further investigation.

Citations

Citations to this article as recorded by

1. Discordance in bone mineral density between lumbar spine and hip in patients with rheumatoid arthritis: A cross-sectional study
Takeshi Mochizuki, Koichiro Yano, Naoko Koenuma, Katsunori Ikari, Ken Okazaki
Osteoporosis and Sarcopenia.2026; 12(2): 98. CrossRef
2. Sex-specific association between lumbar spine-total hip T-score discordance and all-cause mortality: a prospective cohort study from NHANES
Rıdvan Erten, Mehmet Poyrazer
Archives of Osteoporosis.2026;[Epub] CrossRef
3. The observation that older men suffer from hip fracture at DXA T-scores higher than older women and a proposal of a new low BMD category, osteofrailia, for predicting fracture risk in older men
Yì Xiáng J. Wáng, Ben-Heng Xiao, Jason C. S. Leung, James F. Griffith, Maria Pilar Aparisi Gómez, Alberto Bazzocchi, Davide Diacinti, Wing P. Chan, Ali Guermazi, Timothy C. Y. Kwok
Skeletal Radiology.2025; 54(5): 925. CrossRef
4. Assessment of bone turnover markers and DXA parameters to predict bone metastasis progression during zoledronate treatment: a single-center experience
Stella D’Oronzo, Mauro Cives, Eleonora Lauricella, Stefania Stucci, Antonella Centonza, Marica Gentile, Carmela Ostuni, Camillo Porta
Clinical and Experimental Medicine.2024;[Epub] CrossRef
5. Divergent associations of inflammatory markers with bone turnover markers in elderly patients with osteoporotic fractures
Jian Xu, Yue-qin Guo, Shao-han Guo, Min-zhe Xu, Chong Li, Ya-qin Gong, Ke Lu
Scientific Reports.2024;[Epub] CrossRef
6. Different Pattern of T-Score Discordance between Patients with Atypical Femoral Fracture and Femur Neck Fracture
Byung-Ho Yoon, Jang-Won Park, Chan Woo Lee, Young Do Koh
Journal of Bone Metabolism.2023; 30(1): 87. CrossRef

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Poor Dietary Protein Intake in Elderly Population with Sarcopenia and Osteosarcopenia: A Nationwide Population-Based Study: Jun-Il Yoo, Kyung-Hag Lee, Yonghwan Choi, Jaehwang Lee, Yong-Geun Park; J Bone Metab 2020;27(4):301-310.
Published online November 30, 2020; DOI: https://doi.org/10.11005/jbm.2020.27.4.301

Background
Our purpose in this study was to evaluate any deficiency of protein intake for different types of sarcopenia, including osteosarcopenia and sarcopenic obesity and to establish a cut-off value for the relationship between malnutrition, sarcopenia, and osteosarcopenia.
Methods
The cross-sectional study was performed using data from the Korea National Health and Nutrition Examination Survey. A total of 4,020 participants (men, 1,698 and women, 2,322) were analyzed in the present study. Sarcopenia is defined according to the criteria for the Asia Working Group for Sarcopenia. To evaluate the adequacy of protein intake, the value obtained by dividing the amount of protein consumed through food by the daily recommended protein amount (50 g/day) of Korean males was defined as the nutrient intake ratio.
Results
Total protein (P<0.001 in men, P<0.001 in women) and low dietary intake protein (P<0.001 in men, P=0.046 in women) were significantly lower in the sarcopenia group than in the normal group, and were significantly lower in the osteosarcopenia group than in the normal group for both men and women. The cut-off value of the adjusted weight of protein intake for sarcopenia was 0.58 g/kg/day in men and 0.98 g/kg/day in women. The cut-off value for adjusted weight of protein intake for osteo-sarcopenia was 0.8 g/kg/day in men and 0.5 g/kg/day in women.
Conclusions
A comprehensive dietary assessment to detect nutritional deficits that predispose one to or aggravate muscle atrophy is important for establishing a treatment plan for patients with malnutrition.

Citations

Citations to this article as recorded by

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Gita Shafiee, Mehrad Nasiri, Zhaleh Shadman, Mehdi Ebrahimi, Narges Zargar Balajam, Ramin Abdi Dezfouli, Iraj Nabipour, Ramin Heshmat
The Egyptian Journal of Internal Medicine.2025;[Epub] CrossRef
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Minjee Han, Kyung-sook Woo, Kirang Kim
Clinical Nutrition Research.2025; 14(3): 216. CrossRef
7. Effects of Strength Training on Body Composition, Physical Performance, and Protein or Calcium Intake in Older People with Osteosarcopenia: A Meta-Analysis
Jordan Hernandez-Martinez, Braulio Henrique Magnani Branco, Edgar Vasquez-Carrasco, Izham Cid-Calfucura, Tomás Herrera-Valenzuela, Eduardo Guzmán-Muñoz, Pedro Delgado-Floody, Yeny Concha-Cisternas, Pablo Valdés-Badilla
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Sitong Xin, Zibo Wu, Yang Xu, Xiaojing Feng, Yuqi Gao, Yu Han, Jing Zhao, Yuangang Guo, Yan Liu, Fengdan Wang, Bo Li, Xinyao Zhang
Nutrition Journal.2025;[Epub] CrossRef
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Xiaoyan Li, Rongyun Wang, Zhuoer Hou, Qiuhua Sun
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10. Analysis of related factors for sarco-osteoporosis in middle-aged and elderly inpatients and development and validation of a nomogram
Dao Juan Peng, Feng Qiong Gao, Yijiao Lou, Yan Ma, Tongxia Xia
BMC Musculoskeletal Disorders.2024;[Epub] CrossRef
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Runnian Huang, Junwei Hu, Yi Li, Sijia Yang, Xin Li, Tianbo Hou, Zibo Ning, Chunhua Ma, Xiaoyue Yuan, Zheng Wang, Tiantian Zhang, Difei Wang
BMC Geriatrics.2024;[Epub] CrossRef
12. Higher protein intake may benefit in patients with prolonged mechanical ventilation
Chiung-Hsin Chang, Chun-Yu Lin, Yu-Lun Lo, Ting-Yu Lin, Chen-Yiu Hung, Meng-Heng Hsieh, Yueh-Fu Fang, Hung-Yu Huang, Shu-Min Lin, Horng-Chyuan Lin
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Minjee Han, Kyungsook Woo, Kirang Kim
Nutrients.2024; 16(24): 4350. CrossRef
14. Dietary inflammatory potential is associated with sarcopenia in patients with hypertension: national health and nutrition examination study
Jiabin Tu, Shanshan Shi, Yuchen Liu, Jiaming Xiu, Yanbin Zhang, Bo Wu, Ying Liao, Kaihong Chen, Ganyang Li, Llling Chen
Frontiers in Nutrition.2023;[Epub] CrossRef
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Qiaoqiao Du, Yanhui Lu, Fan Hu, Xinglin Feng, Yunquan Zhang, Shaojie Li, Chi Zhang, Hua Zhang, Yi Zeng, Yao Yao, Zhaohui Lu, Wenya Zhang, Xiangyang Gao
Frontiers in Nutrition.2023;[Epub] CrossRef
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Scientific Reports.2022;[Epub] CrossRef
17. Change of Computed Tomography-Based Body Composition after Adrenalectomy in Patients with Pheochromocytoma
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Cancers.2022; 14(8): 1967. CrossRef
18. Decreased Serum Level of Sclerostin in Older Adults with Sarcopenia
Seong Hee Ahn, Hee-Won Jung, Eunju Lee, Ji Yeon Baek, Il-Young Jang, So Jeong Park, Jin Young Lee, Eunah Choi, Yun Sun Lee, Seongbin Hong, Beom-Jun Kim
Endocrinology and Metabolism.2022; 37(3): 487. CrossRef
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Beom-Jun Kim
Annals of Geriatric Medicine and Research.2022; 26(2): 63. CrossRef
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Sarcopenic Obesity in Elderly Korean Women: A Nationwide Cross-sectional Study: Young Nam Kwon, Sung Sang Yoon, Kyung-Hag Lee; J Bone Metab 2018;25(1):53-58.
Published online February 28, 2018; DOI: https://doi.org/10.11005/jbm.2018.25.1.53

Background

Sarcopenia causes loss of muscle mass in the elderly and is associated with development of metabolic syndrome in those with obesity. This study evaluated the prevalence of sarcopenic obesity (SO) in healthy Korean elderly women.

Methods

This study was based on data from the Korea National Health and Nutrition Examination Survey IV and V, 2008–2011. Whole body dual energy X-ray absorptiometry and body mass index measurement were performed for all patients. Women aged 65 years or older were included in this study. Total appendicular extremity muscle mass was used to determine the skeletal muscle mass index.

Results

Of 2,396 women aged 65 years or older, a total of 1,491 (62.2%) were underweight, normal weight, or overweight, while 905 (37.8%) were obese. The prevalence of sarcopenia using a cut-off value of 5.4 kg/m² was 64.9% (63/97) in underweight women, 38.2% (320/838) in normal weight women, 17.1% (95/556) in overweight women, and 6.1% (55/905) in obese women.

Conclusions

The prevalence of sarcopenia was different among groups. The prevalence rate in obese women was lower than that in non-obese women. SO is a new category of obesity in older adults with high adiposity coupled with low muscle mass. The prevalence of SO was lower than that in previous studies because of differences in the definition. A consensus definition of SO needs to be established.

Citations

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Do-Youn Lee
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Cureus.2024;[Epub] CrossRef
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Erratum

Erratum to: Vitamin D Deficiency Is Highly Concomitant but Not Strong Risk Factor for Mortality in Patients Aged 50 Year and Older with Hip Fracture: Kyung-Hag Lee, Jung-Won Lim, Yong-Gum Park, Yong-Chan Ha; J Bone Metab 2016;23(1):49-49.
Published online February 29, 2016; DOI: https://doi.org/10.11005/jbm.2016.23.1.49

Citations

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1. Adjuvant Vitamin D Injection in Elderly Patients Before Intertrochanteric Fracture Surgery: A Randomised Controlled Trial
Mehrdad Rabiee Rad, Ghazal Ghasempour Dabaghi, Alireza Afshari Safavi, Pooya Moshkdar, Hossein Akbariaghdam
Geriatric Orthopaedic Surgery & Rehabilitation.2024;[Epub] CrossRef