Skip to main navigation Skip to main content
  • KSBMR

JBM : Journal of Bone Metabolism

OPEN ACCESS
ABOUT
BROWSE ARTICLES
EDITORIAL POLICIES
FOR CONTRIBUTORS

Page Path

11
results for

"Hee-Sook Lim"

Article category

Keywords

Publication year

Authors

"Hee-Sook Lim"

Original Articles

Association of Dietary Variety Status and Sarcopenia in Korean Elderly
Hee-Sook Lim
J Bone Metab 2020;27(2):143-149.
Published online May 31, 2020
DOI: https://doi.org/10.11005/jbm.2020.27.2.143
Background

Sarcopenia is associated with a variety of factors including age, diseases, exercise, and heredity. In particular, diet is known to affect changes in muscle mass loss.

Methods

The purpose of this study was to analyze the diversity of food intake according to the presence of sarcopenia in elderly people over 65 years old using the 2008 to 2011 Korea National Health and Nutrition Examination Survey. The differences in subjects' general characteristics, lifestyle, and intake of 15 food groups were compared, and the risk odds ratio (OR) for sarcopenia was calculated for each food intake by gender.

Results

The proportion of sarcopenia was 27.7% for males and 24.3% for females. The sarcopenia group had significantly lower intakes of nuts and seeds, meats, and milks than the non-sarcopenia group in males. The females had significantly lower intake of fruits, milks, and beverages in non-sarcopenia group. The dietary diversity score was significantly lower in females with sarcopenia than non-sarcopenia group. Regression analysis of the risk OR for sarcopenia according to food group intake showed that the subjects in the lowest tertile (<31.1 g) had a 1.83 times (95% confidence interval [CI], 1.13–2.42) risk for sarcopenia in males. In case of milks intake of females, the risk for sarcopenia increased 1.39 times (95% CI, 1.11–1.86) in subjects with the lowest tertile (<30.1 g).

Conclusions

Dietary diversity status was the most vulnerable to female with sarcopenia. Sarcopenia was associated with meat intake in male and milk intake in female.

Citations

Citations to this article as recorded by  Crossref logo
  • 1. Association between dietary diversity and healthy aging: a systematic review
    Roghayeh Molani-Gol, Maryam Rafraf, Beitullah Alipour
    BMC Nutrition.2025;[Epub]     CrossRef
  • 2. Exploring the Relationship Among Malnutrition, Intake of Various Food Groups, and Sarcopenia in Elderly Population: A Cross‐Sectional Analysis
    Mohammad Mehdi Mousavi Nasab, Armin Khavandegar, Hossein Fakhrzadeh, Mitra Moodi, Keyvan Karimi, Sarmad Salehi, Masoumeh Khorashadizadeh, Hanieh‐Sadat Ejtahed, Farshad Sharifi
    Health Science Reports.2025;[Epub]     CrossRef
  • 3. Influence of exercise and nutrition on sarcopenia in cardiovascular disease: a Scientific Statement of the European Association of Preventive Cardiology of the European Society of Cardiology
    Veronique Cornelissen, Henner Hanssen, Christopher Hurst, Raphael Knaier, Elena Marques-Sule, Trine Moholdt, Daniel Neunhaeuserer, Kristina Norman, Roberto Pedretti, Annett Salzwedel, Kai Savonen, T Scott Bowen
    European Journal of Preventive Cardiology.2025;[Epub]     CrossRef
  • 4. Associations between Dietary Diversity Scores and Chronic Kidney Disease-related Sarcopenia: A Case-control Study
    E Tarighi, A.R Dorosty Motlagh, A Djazayery, M Safavian
    Journal of Nutrition Sciences and Food Technology.2024; 19(2): 11.     CrossRef
  • 5. Mediating effects of physical activities and cognitive function on the relationship between dietary diversity and all-cause mortality in community-dwelling older adults
    Chi Zhang, Anying Bai, Guoqing Fan, Ji Shen, Yuting Kang, Pengjun Zhang
    Journal of Global Health.2024;[Epub]     CrossRef
  • 6. Incretin-Based Therapies: A Promising Approach for Modulating Oxidative Stress and Insulin Resistance in Sarcopenia
    Raniah I. Alnaser, Fawaz A. Alassaf, Mohammed N. Abed
    Journal of Bone Metabolism.2024; 31(4): 251.     CrossRef
  • 7. The association between healthy beverage index and sarcopenic obesity among women with overweight and obesity: a cross-sectional study
    Niloufar Rasaei, Rasool Ghaffarian-Ensaf, Fatemeh Gholami, Farideh Shiraseb, Alireza Khadem, Seyedeh Fatemeh Fatemi, Khadijeh Mirzaei
    BMC Endocrine Disorders.2023;[Epub]     CrossRef
  • 8. Mediterranean Diet and Sarcopenia Features in Apparently Healthy Adults over 65 Years: A Systematic Review
    Sousana K. Papadopoulou, Paraskevi Detopoulou, Gavriela Voulgaridou, Despoina Tsoumana, Maria Spanoudaki, Faviola Sadikou, Vasiliki G. Papadopoulou, Christiana Zidrou, Ioanna P. Chatziprodromidou, Constantinos Giaginis, Pantelis Nikolaidis
    Nutrients.2023; 15(5): 1104.     CrossRef
  • 9. Dietary diversity predicts the mortality among older people: Data from the fifth Thai national health examination survey
    Chalobol Chalermsri, Syed Moshfiqur Rahman, Eva-Charlotte Ekström, Shirin Ziaei, Wichai Aekplakorn, Warapone Satheannopakao, Weerasak Muangpaisan
    Archives of Gerontology and Geriatrics.2023; 110: 104986.     CrossRef
  • 10. Effects of Turmeric Extract on Age-Related Skeletal Muscle Atrophy in Senescence-Accelerated Mice
    Weida Lyu, Marika Kousaka, Huijuan Jia, Hisanori Kato
    Life.2023; 13(4): 941.     CrossRef
  • 11. Prosthodontic treatment can improve the ingestible food profile in Japanese adult outpatients
    Aya Kimura-Ono, Kenji Maekawa, Takuo Kuboki, Kumiko Nawachi, Masanori Fujisawa, Hironobu Sato, Hideki Aita, Shigeto Koyama, Masayuki Hideshima, Yuji Sato, Hiroyuki Wake, Kan Nagao, Yorika Kodaira-Ueda, Katsushi Tamaki, Shinsuke Sadamori, Kazuhiro Tsuga, Y
    Journal of Prosthodontic Research.2023; 67(2): 189.     CrossRef
  • 12. Dietary diversity and possible sarcopenia among older people in China: a nationwide population-based study
    Qiaoqiao Du, Yanhui Lu, Fan Hu, Xinglin Feng, Yunquan Zhang, Shaojie Li, Chi Zhang, Hua Zhang, Yi Zeng, Yao Yao, Zhaohui Lu, Wenya Zhang, Xiangyang Gao
    Frontiers in Nutrition.2023;[Epub]     CrossRef
  • 13. Association of diet quality with the risk of Sarcopenia based on the Chinese diet balance index 2016: a cross-sectional study among Chinese adults in Henan Province
    Xiaodong Ran, Junya Zhai, Minmin Xu, Xiaoxi Zhu, Amin Ullah, Quanjun Lyu
    BMC Public Health.2023;[Epub]     CrossRef
  • 14. The Relationship between the Characteristics of Low Phase Angle and Food Groups Consumed in Community-dwelling Older Women
    Chika Momoki, Taeko Tsuji, Daiki Habu
    The Japanese Journal of Nutrition and Dietetics.2023; 81(6): 279.     CrossRef
  • 15. Diet quality and a traditional dietary pattern predict lean mass in Australian women: Longitudinal data from the Geelong Osteoporosis Study
    Jessica A. Davis, Mohammadreza Mohebbi, Fiona Collier, Amy Loughman, Nitin Shivappa, James R. Hébert, Julie A. Pasco, Felice N. Jacka
    Preventive Medicine Reports.2021; 21: 101316.     CrossRef
  • 16. Nuts and Older Adults’ Health: A Narrative Review
    Sze-Yen Tan, Siew Ling Tey, Rachel Brown
    International Journal of Environmental Research and Public Health.2021; 18(4): 1848.     CrossRef
  • 17. Sex Differences in the Association between Living Environmental Factors and Nutritional Status in Community-Dwelling Elderly Koreans
    Dong Eun Kim, Hee-Sook Lim, Hyejin Ahn, Young Sun Kim, Yoo Kyoung Park
    International Journal of Environmental Research and Public Health.2020; 17(17): 6034.     CrossRef
  • 8,023 View
  • 135 Download
  • Crossref
Is There a Difference in Serum Vitamin D Levels and Bone Mineral Density According to Body Mass Index in Young Adult Women?
Hee-Sook Lim, Dong Won Byun, Kyo Il Suh, Hyeong Kyu Park, Hye Jeong Kim, Tae-Hee Kim, Hae-Hyeog Lee
J Bone Metab 2019;26(3):145-150.
Published online August 31, 2019
DOI: https://doi.org/10.11005/jbm.2019.26.3.145
Background

In the life cycle, bone mineral density (BMD) is the most optimal condition in the 20s. In Korea, vitamin D deficiency status is very serious in Korean women due to recent lack of activity, weight polarization, and inadequate nutritional intake. The purpose of this study was to compare serum vitamin D and BMD according to obesity status in Korean young adult women.

Methods

A total of 143 female college students participated in the research. Body fat and lean body status were analyzed using a body composition analyzer. Nutrient intakes of the subjects were assessed by 3-days food record method. The BMDs was measured by dual energy X-ray absorptiometry. The subjects were divided into normal weight group and obesity group on their body mass index.

Results

Obesity group showed significantly higher weight, body fat (%), and body fat (kg) than normal weight group and T-scores of lumbar-2 spines were significantly lower. Obesity group showed high triglyceride and low-density lipoprotein cholesterol levels and vitamin D levels were significantly lower. Physical fitness and activity status showed that sit and reach and sit up were significantly lower in obesity group. The intake of carbohydrates was higher in the obesity group than in the normal weight group, and the intake of vitamin C and vitamin D was significantly lower. Factors affecting serum vitamin D were analyzed as body fat (%), lumbar-2 T-score, triglyceride, and carbohydrate intake.

Conclusions

Obese women need more effort to manage their serum vitamin D status and balanced nutrition to prevent bone loss.

Citations

Citations to this article as recorded by  Crossref logo
  • 1. Bone turnover markers and bone mineral density in prepubertal obese children
    Ola Taha, Amany Elhwary, Sarah M. Shoeib, Yosra Fouad Mohammed Rashad, Dina Ata
    Paediatrica Indonesiana.2024; 64(6): 473.     CrossRef
  • 2. 25-hydroxyvitamin D in older adults: Which factors really matter?
    Lucas Baptistella Barbieri, Marco Aurélio Costa da Silva, Fabiana de Souza Orlandi, Ariene Angelini dos Santos-Orlandi, Sofia Cristina Iost Pavarini, Karina Gramani-Say, Grace Angélica de Oliveira Gomes, Marisa S. Zazzetta, Henrique Pott-Junior
    Geriatric Nursing.2022; 44: 84.     CrossRef
  • 3. Changes in bone mass associated with obesity and weight loss in humans: Applicability of animal models
    Vivi F.H. Jensen, Anne-Marie Mølck, Majken Dalgaard, Fiona E. McGuigan, Kristina E. Akesson
    Bone.2021; 145: 115781.     CrossRef
  • 4. Bone Marrow Fat Measured by a Chemical Shift‐Encoded Sequence (IDEAL‐IQ) in Patients With and Without Metabolic Syndrome
    Qiang Ma, Xiaoyue Cheng, Xinmeng Hou, Zhenghan Yang, Daqing Ma, Zhenchang Wang
    Journal of Magnetic Resonance Imaging.2021; 54(1): 146.     CrossRef
  • 5. Association between obesity and risk of fracture, bone mineral density and bone quality in adults: A systematic review and meta-analysis
    Anne-Frédérique Turcotte, Sarah O’Connor, Suzanne N. Morin, Jenna C. Gibbs, Bettina M. Willie, Sonia Jean, Claudia Gagnon, Tuan Van Nguyen
    PLOS ONE.2021; 16(6): e0252487.     CrossRef
  • 6. Vitamin D Level Trajectories of Adolescent Patients with Anorexia Nervosa at Inpatient Admission, during Treatment, and at One Year Follow Up: Association with Depressive Symptoms
    Manuel Föcker, Nina Timmesfeld, Judith Bühlmeier, Denise Zwanziger, Dagmar Führer, Corinna Grasemann, Stefan Ehrlich, Karin Egberts, Christian Fleischhaker, Christoph Wewetzer, Ida Wessing, Jochen Seitz, Beate Herpertz-Dahlmann, Johannes Hebebrand, Lars L
    Nutrients.2021; 13(7): 2356.     CrossRef
  • 7. Obesity and Bone Health: A Complex Link
    Jing Hou, Chen He, Wenzhen He, Mi Yang, Xianghang Luo, Changjun Li
    Frontiers in Cell and Developmental Biology.2020;[Epub]     CrossRef
  • 5,734 View
  • 62 Download
  • Crossref
Comparison of Health Status and Nutrient Intake by Household Type in the Elderly Population
Hee-Sook Lim, Mi-Nam Lee
J Bone Metab 2019;26(1):25-30.
Published online February 28, 2019
DOI: https://doi.org/10.11005/jbm.2019.26.1.25
Background

The health condition of old age is affected by various factors such as economic level, disease condition, and nutrition. With the aging population in Korea, the ratio of single-person households increased rapidly. Research on the health status and nutrition of the elderly in the single-person household is very insufficient. In this study, we compared the health and nutritional status of the elderly by the household type.

Methods

Data from the 2013 to 2014 Korea National Health and Nutrition Examination Survey were used. A total of 2,730 patients were classified into 2 groups (single-person, with family), and general, chronic disease, health behavior, nutrient intake, and food insecurity status were compared by the statistical analysis.

Results

Single-person households had a low economic and educational level and a higher percentage of women. In addition, obesity, hypertension, dyslipidemia, stroke, myocardial infarction disease rate was significantly higher. Sing-person households answered that their subjective health status was bad, and their quality of life was low. As a result of analysis of the quality of the diet in the single-person, the intake of protein, calcium, iron, vitamin B2, niacin, and vitamin C was significantly lower. In particular, the intake of calcium was the most insufficient. Food insecurity has also been observed, including the inability to consume diverse and sufficient foods due to economic difficulties.

Conclusions

More attention should be paid to the health of single-person households in elderly population and various policies should be prepared.

Citations

Citations to this article as recorded by  Crossref logo
  • 1. Comparison of dietary behaviors and nutrient intake by gender and household type among older Koreans: a cross-sectional study using data from the 8th Korea National Health and Nutrition Examination Survey
    Dana Park, Soo-Kyung Lee
    Korean Journal of Community Nutrition.2026; 31(1): 87.     CrossRef
  • 2. The Association of Oral Processing Factors and Nutrient Intake in Community-Dwelling Older Adults: A Systematic Review and Meta-Analysis
    Supatchayaporn Nitsuwat, James Webster, Anwesha Sarkar, Janet Cade
    Nutrition Reviews.2025; 83(3): e762.     CrossRef
  • 3. Risk of End-Stage Kidney Disease in Individuals with Diabetes Living Alone: A Large-Scale Population-Based Study
    Kyunghun Sung, Jae-Seung Yun, Bongseong Kim, Hun-Sung Kim, Jae-Hyoung Cho, Yong-Moon Mark Park, Kyungdo Han, Seung-Hwan Lee
    Diabetes & Metabolism Journal.2025; 49(4): 862.     CrossRef
  • 4. Depressive symptoms among single-person households: roles of dietary habits and frequency of eating meals with others
    Soyoung Lee, Hyewon Park, Chung Ho Kim, Bomi Park
    SSM - Population Health.2025; 31: 101856.     CrossRef
  • 5. Health-related quality of life of single-person households in the United States: results from the 2014–2023 Behavioral Risk Factor Surveillance System
    Seonkyeong Yang, Ilsoo Park, Hyun Jin Song
    Quality of Life Research.2025; 34(12): 3663.     CrossRef
  • 6. Biopsychosocial factors of quality of life among middle-aged adults living alone in South Korea: a secondary data analysis using the 2017 Korea Community Health Survey
    Hyerang Kim, Eun Jung Bae, Yunkyung Choi, Heesook Son
    Archives of Public Health.2024;[Epub]     CrossRef
  • 7. All-cause and cause-specific mortality risks in individuals with diabetes living alone: A large-scale population-based cohort study
    Jae-Seung Yun, Kyungdo Han, Bongseong Kim, Seung-Hyun Ko, Hyuk-Sang Kwon, Yu-Bae Ahn, Yong-Moon Mark Park, Seung-Hwan Lee
    Diabetes Research and Clinical Practice.2024; 217: 111876.     CrossRef
  • 8. Gender Differences in Consumer Debt Stress: Impacts on Job Performance, Family Life and Health
    Lucia F. Dunn, Ida A. Mirzaie
    Journal of Family and Economic Issues.2023; 44(3): 550.     CrossRef
  • 9. Changes in nutritional status of Korean older adults during COVID-19 Pandemic by household income and demographic factors-using the Korea National Health and Nutrition Examination Survey(2019-2020): a cross-sectional study
    You-Sin Lee, Yoonna Lee
    Korean Journal of Community Nutrition.2023; 28(4): 302.     CrossRef
  • 10. Malnutrition, Family Support, and Possible Sarcopenia in Patients Undergoing Transcatheter Aortic Valve Implantation
    Ching-I Hsu, Jeng Wei, Heng-Hsin Tung, Li-Ning Peng, Liang-Kung Chen, Chieh-Yu Liu
    Journal of Cardiovascular Nursing.2021; 36(6): 565.     CrossRef
  • 11. Sex Differences in the Association between Living Environmental Factors and Nutritional Status in Community-Dwelling Elderly Koreans
    Dong Eun Kim, Hee-Sook Lim, Hyejin Ahn, Young Sun Kim, Yoo Kyoung Park
    International Journal of Environmental Research and Public Health.2020; 17(17): 6034.     CrossRef
  • 12. Risk factors, incidence, and prevalence of diabetes among rural farm and non-farm residents of Saskatchewan, Canada; a population-based longitudinal cohort study
    Md Saiful Alam, Roland Dyck, Bonnie Janzen, Chandima Karunanayake, James Dosman, Punam Pahwa
    Journal of Diabetes & Metabolic Disorders.2020; 19(2): 1563.     CrossRef
  • 5,362 View
  • 47 Download
  • Crossref
Association between Sarcopenia, Sarcopenic Obesity, and Chronic Disease in Korean Elderly
Hee-Sook Lim, Yoon-Hyung Park, Kyoil Suh, Myung Hi Yoo, Hyeong Kyu Park, Hye Jeong Kim, Jae-Hyuk Lee, Dong-Won Byun
J Bone Metab 2018;25(3):187-193.
Published online August 31, 2018
DOI: https://doi.org/10.11005/jbm.2018.25.3.187
Background

It is a very important social issue for Korea to have a healthy old age as an aged society. Aging causes a lot of physical changes, especially sarcopenia. Sarcopenia is defined as a persistent decrease in skeletal muscle and muscle strength. Sarcopenic obesity is a phenomenon in which fat is replaced instead of muscle. The purpose of this study was to examine the prevalence of sarcopenia and sarcopenic obesity in Korean elderly and to analyze the relationship with chronic disease.

Methods

Data from the 2008 to 2011 the Korea National Health and Nutrition Survey were used. A total of 3,492 patients were classified into 3 groups (non-sarcopenia, sarcopenia, sarcopenic obesity), and general, anthropometry, health behavior, nutrient intake and chronic disease status were compared by the statistical analysis.

Results

The rate of moderate exercise was significantly lower in the sarcopenia and sarcopenic-obesity group than in the non-sarcopenia group (P=0.007). The sarcopenic obesity group had significantly higher energy (P=0.005), protein (P=0.046) and fat (P=0.001) intake than the sarcopenic group. The sarcopenic-obesity group had the highest ratio of diabetes (P=0.023) and dyslipidemia (P=0.004) in the 3 groups. Compared with the non-sarcopenia group, in the sarcopenia and sarcopenic obesity groups, the odds ratios (ORs) of diabetes was increased by 1.24 and 2.16 while the ORs of dyslipidemia was increased by 1.12 and 1.50, respectively.

Conclusions

Regular exercise and adequate nutrient intake (energy, protein and fat) are essential for the prevention of sarcopenia in Korean elderly, and management of chronic disease in sarcopenic obesity elderly is important.

Citations

Citations to this article as recorded by  Crossref logo
  • 1. Adipose dysfunction, lipid dysregulation, and adipokines in sarcopenia: a systematic review and meta-analysis with sex-specific analyses
    Djandan Tadum Arthur Vithran, Mahamat Hassan Yacoub Hassan, Masoud Rahmati, Laurent Boyer, Awil Abdi Wehliye, Wenfeng Xiao, Yusheng Li
    Age and Ageing.2026;[Epub]     CrossRef
  • 2. Relationship between physical function and sarcopenia in the older adults from Amazonas: A cross-sectional study
    Alex Barreto de Lima, Duarte Henrinques-Neto, David Scott, André de Araújo Pinto, Gustavo dos Santos Ribeiro, Miguel Peralta, Kessketlen Alves Miranda, Pedro Campos, Elvio Rúbio Gouveia, Jeremy P Loenneke
    PLOS ONE.2025; 20(3): e0320079.     CrossRef
  • 3. Association Between Protein Intake and Sarcopenia-Related Indicators Among Korean Older Adults: A Scoping Review
    Minjee Han, Kyung-sook Woo, Kirang Kim
    Clinical Nutrition Research.2025; 14(3): 216.     CrossRef
  • 4. Criteria of frail older people with type 2 diabetes who are suitable for SGLT-2 inhibitors and GLP-1RA therapy
    A.H. Abdelhafiz, I. Siqueira, A.J. Sinclair
    Journal of Diabetes and its Complications.2025; 39(12): 109193.     CrossRef
  • 5. Predictive effect of the triglyceride glucose index on abnormal blood glucose metabolism events in populations with sarcopenia: a cross-sectional study
    Yingying Zhu, Jiabei He, Xin Li, Yunping Xu, Jingshuang He, Liang Li
    BMC Endocrine Disorders.2025;[Epub]     CrossRef
  • 6. Associations between upper limb flexibility and all-cause mortality in the oldest-old
    Yushan Zhang, Chi Zhang, Jia Hu, Yuting Kang, Jie Zhang, Jianliang Zhao, Hong Shi, Ji Shen
    Journal of Global Health.2025;[Epub]     CrossRef
  • 7. Prevalence, diagnosis and treatment of sarcopenic obesity in older adults: a systematic review and a meta-analysis
    Gözde Şengül Ayçiçek, Arzu Okyar Baş, Erdem Karabulut, Meltem Gülhan Halil
    Acta Clinica Belgica.2025; 80(6): 226.     CrossRef
  • 8. Bioactive Nutritional Components Within the Planetary Health Diet for Preventing Sarcopenic Obesity and Diabetic Sarcopenia: A Systematic Review
    Lia Elvina, Chiao-Ming Chen, Dang Hien Ngan Nguyen, Chun-Che Wei, Chien-Tien Su, Te-Chao Fang, Fandi Sutanto, Sing-Chung Li
    Nutrients.2025; 17(23): 3656.     CrossRef
  • 9. Muscle strength and the risk of Multimorbidity in Middle-aged and older Chinese adults: A prospective cohort study
    Zhuofan Zhang, Lin Zhu, Zekai Chen
    Aging Clinical and Experimental Research.2025;[Epub]     CrossRef
  • 10. Obesity paradox in older sarcopenic adults ― a delay in aging: A systematic review and meta-analysis
    Szimonetta Eitmann, Peter Matrai, Peter Hegyi, Marta Balasko, Balint Eross, Kira Dorogi, Erika Petervari
    Ageing Research Reviews.2024; 93: 102164.     CrossRef
  • 11. Sarcopenia and risk factors among Japanese community‐dwelling older adults during the COVID‐19 pandemic: A cross‐sectional study
    Natsuka Ogawa, Shan Yun, Miku Izutsu, Michiko Yuki
    Nursing & Health Sciences.2024;[Epub]     CrossRef
  • 12. Dyslipidemia is associated with sarcopenia of the elderly: a meta-analysis
    Bingqing Bi, Xinying Dong, Meilin Yan, Zhuo Zhao, Ruitong Liu, Shugang Li, Hao Wu
    BMC Geriatrics.2024;[Epub]     CrossRef
  • 13. Effect of Sarcopenia on 10-Year Risk of Atherosclerotic Cardiovascular Disease in Patients with Type 2 Diabetes Mellitus
    Long-Fei Xia, Jing-Bo Li, Guo-Sheng Tian, Wei-Ran Jiang, Yao-Shuang Li, Chen-Ying Lin, Hui-Na Qiu, Fan Wu, Jun-Jia Wang, Chun-Jun Li, Jing-Na Lin
    Diabetes, Metabolic Syndrome and Obesity.2024; Volume 17: 1621.     CrossRef
  • 14. Sex-Specific Effects of Dietary Factors on Sarcopenic Obesity in Korean Elderly: A Nationwide Cross-Sectional Study
    Soojeong Kim, Kyung Hee Hong
    Nutrients.2024; 16(8): 1175.     CrossRef
  • 15. Prevalence of sarcopenic obesity in the older non-hospitalized population: a systematic review and meta-analysis
    Yuhong Luo, Yanqiu Wang, Shuao Tang, Ludan Xu, Xinyu Zhao, Mengya Han, Yuhua Liu, Yan Xu, Binru Han
    BMC Geriatrics.2024;[Epub]     CrossRef
  • 16. Machine‐learning classifier models for predicting sarcopenia in the elderly based on physical factors
    Jun‐hee Kim
    Geriatrics & Gerontology International.2024; 24(6): 595.     CrossRef
  • 17. Blood Flow Restriction Training: Physiological Effects, Molecular Mechanisms, and Clinical Applications
    Sebastián Rodríguez, María Fernanda Rodríguez-Jaime, Catalina León-Prieto
    Critical Reviews in Physical and Rehabilitation Medicine.2024; 36(4): 13.     CrossRef
  • 18. Protective Effects of Cervus elaphus and Eucommia ulmoides Mixture (KGC01CE) on Muscle Loss and Function in Aged Rats
    Gi-Bang Koo, Han Ol Kwon, Jong Han Kim, Seung Ho Lee, Sung Lye Shim, Kyoung Hwa Jang
    Current Issues in Molecular Biology.2024; 46(10): 11190.     CrossRef
  • 19. Rodent model intervention for prevention and optimal management of sarcopenia: A systematic review on the beneficial effects of nutrients & non-nutrients and exercise to improve skeletal muscle health
    Vijayakumar Mayakrishnan, Priya Kannappan, Janani Balakarthikeyan, Choon Young Kim
    Ageing Research Reviews.2024; 102: 102543.     CrossRef
  • 20. Relationship between Serum Ferritin Levels and Sarcopenia in Transfusion-Dependent Thalassemia Patient
    Rendra Prasetya Saefudin, Siprianus Ugroseno Yudho Bintoro, Sony Wibisono Mudjanarko, Merlyna Savitri, Lukita Pradhevi, Agustinus Vincent, Michael Austin Pradipta Lusida, Kartika Afrida Fauzia
    Biomolecular and Health Science Journal.2024; 7(2): 125.     CrossRef
  • 21. Association of Protein Intake with Sarcopenia and Related Indicators Among Korean Older Adults: A Systematic Review and Meta-Analysis
    Minjee Han, Kyungsook Woo, Kirang Kim
    Nutrients.2024; 16(24): 4350.     CrossRef
  • 22. Deciphering the “obesity paradox” in the elderly: A systematic review and meta‐analysis of sarcopenic obesity
    Chaoran Liu, Pui Yan Wong, Yik Lok Chung, Simon Kwoon‐Ho Chow, Wing Hoi Cheung, Sheung Wai Law, Juliana Chung Ngor Chan, Ronald Man Yeung Wong
    Obesity Reviews.2023;[Epub]     CrossRef
  • 23. Association between Sarcopenic Obesity Status and Nonalcoholic Fatty Liver Disease and Fibrosis
    Wolhwa Song, Sung Hwan Yoo, Jinsun Jang, Su Jung Baik, Byoung Kwon Lee, Hyun Woong Lee, Jong Suk Park
    Gut and Liver.2023; 17(1): 130.     CrossRef
  • 24. The effect of combining nutrient intake and physical activity levels on central obesity, sarcopenia, and sarcopenic obesity: a population-based cross-sectional study in South Korea
    Jong Eun Park, Seulgi Lee, Kirang Kim
    BMC Geriatrics.2023;[Epub]     CrossRef
  • 25. Relationship between Body Composition and Arterial Stiffness in Korean Adults
    Hye-Jin Jang, Hyun-Min Koh, Ji-Yong Jang, Hae-Jeong Lee, Jin-Sook Moon, Jeong-Min Ji, Anna Lee
    Korean Journal of Family Practice.2023; 13(1): 23.     CrossRef
  • 26. Sarcopenia and Cognitive Decline in Older Adults: Targeting the Muscle–Brain Axis
    Beatrice Arosio, Riccardo Calvani, Evelyn Ferri, Hélio José Coelho-Junior, Angelica Carandina, Federica Campanelli, Veronica Ghiglieri, Emanuele Marzetti, Anna Picca
    Nutrients.2023; 15(8): 1853.     CrossRef
  • 27. Sarcopenia Prediction for Elderly People Using Machine Learning: A Case Study on Physical Activity
    Minje Seok, Wooseong Kim
    Healthcare.2023; 11(9): 1334.     CrossRef
  • 28. A scientometric analysis of sarcopenic obesity: Future trends and new perspectives
    Duygu Tutan, Ülkem Şen Uzeli
    Medicine.2023; 102(26): e34244.     CrossRef
  • 29. Obesity in the elderly: peculiarities of treatment in outpatient practice
    L. A. Suplotova, O. O. Alieva, T. S. Dushina, O. B. Makarova
    Obesity and metabolism.2023; 20(2): 140.     CrossRef
  • 30. Associations between physical activity, physical fitness, and body composition in adults living in Germany: A cross-sectional study
    Raphael Schilling, Steffen C. E. Schmidt, Janis Fiedler, Alexander Woll, Melissa M. Markofski
    PLOS ONE.2023; 18(10): e0293555.     CrossRef
  • 31. Machine Learning for Sarcopenia Prediction in the Elderly Using Socioeconomic, Infrastructure, and Quality-of-Life Data
    Minje Seok, Wooseong Kim, Jiyoun Kim
    Healthcare.2023; 11(21): 2881.     CrossRef
  • 32. Sarcopenic Obesity as a Risk Factor for Cardiovascular Disease: An Underrecognized Clinical Entity
    Aditya John Binu, Nitin Kapoor, Saptarshi Bhattacharya, Kamal Kishor, Sanjay Kalra
    Heart International.2023; 17(2): 6.     CrossRef
  • 33. Sarcopenic Obesity as a Risk Factor for Cardiovascular Disease: An Underrecognized Clinical Entity
    Aditya John Binu, Nitin Kapoor, Saptarshi Bhattacharya, Kamal Kishor, Sanjay Kalra
    Heart International.2023; 17(2): 6.     CrossRef
  • 34. Impact of Sarcopenia on the Severity of the Liver Damage in Patients With Non-alcoholic Fatty Liver Disease
    Vittoria Zambon Azevedo, Cristina Alina Silaghi, Thomas Maurel, Horatiu Silaghi, Vlad Ratziu, Raluca Pais
    Frontiers in Nutrition.2022;[Epub]     CrossRef
  • 35. Association between platelet, white blood cell count, platelet to white blood cell ratio and sarcopenia in community-dwelling older adults: focus on Bushehr Elderly Health (BEH) program
    Mohamad Gholizade, Akram Farhadi, Maryam Marzban, Mehdi Mahmudpour, Iraj Nabipour, Mohammadreza Kalantarhormozi, Gita Shafiee, Afshin Ostovar, Bagher Larijani, Amir Hossein Darabi, Eisa Safavi
    BMC Geriatrics.2022;[Epub]     CrossRef
  • 36. Hypoglycaemic therapy in frail older people with type 2 diabetes mellitus—a choice determined by metabolic phenotype
    Alan J. Sinclair, Daniel Pennells, Ahmed H. Abdelhafiz
    Aging Clinical and Experimental Research.2022; 34(9): 1949.     CrossRef
  • 37. Molecular Mechanisms of Inflammation in Sarcopenia: Diagnosis and Therapeutic Update
    Guadalupe Elizabeth Jimenez-Gutierrez, Laura Edith Martínez-Gómez, Carlos Martínez-Armenta, Carlos Pineda, Gabriela Angélica Martínez-Nava, Alberto Lopez-Reyes
    Cells.2022; 11(15): 2359.     CrossRef
  • 38. Effects of three modes of physical activity on physical fitness and hematological parameters in older people with sarcopenic obesity: A systematic review and meta-analysis
    Min Zhuang, Mengdie Jin, Tijiang Lu, Linqian Lu, Barbara E. Ainsworth, Yu Liu, Nan Chen
    Frontiers in Physiology.2022;[Epub]     CrossRef
  • 39. Association between Sarcopenia and Energy and Protein Intakes in Community-dwelling Elderly
    Woori Na, Dayoung Oh, Seohyeon Hwang, Bonghee Chung, Cheongmin Sohn
    Korean Journal of Community Nutrition.2022; 27(4): 286.     CrossRef
  • 40. Low Skeletal Muscle Mass Accompanied by Abdominal Obesity Additively Increases the Risk of Incident Type 2 Diabetes
    Ji Eun Jun, Seung-Eun Lee, You-Bin Lee, Gyuri Kim, Sang-Man Jin, Jae Hwan Jee, Jae Hyeon Kim
    The Journal of Clinical Endocrinology & Metabolism.2022;[Epub]     CrossRef
  • 41. Lower body muscle strength, dynapenic obesity and risk of type 2 diabetes –longitudinal results on the chair-stand test from the Survey of Health, Ageing and Retirement in Europe (SHARE)
    Bernd Kowall
    BMC Geriatrics.2022;[Epub]     CrossRef
  • 42. Prevalence of Sarcopenic Obesity in Various Comorbidities, Diagnostic Markers, and Therapeutic Approaches: A Review
    Mangalam Kumari, Archana Khanna
    Annals of Geriatric Medicine and Research.2022; 26(4): 296.     CrossRef
  • 43. Relationship between low skeletal muscle mass, sarcopenic obesity and left ventricular diastolic dysfunction in Korean adults
    Jee Hee Yoo, Sung Woon Park, Ji Eun Jun, Sang‐Man Jin, Kyu Yeon Hur, Moon‐Kyu Lee, Mira Kang, Gyuri Kim, Jae Hyeon Kim
    Diabetes/Metabolism Research and Reviews.2021;[Epub]     CrossRef
  • 44. Equivalent servings of free-range reindeer promote greater net protein balance compared to commercial beef
    Melynda S. Coker, Scott E. Schutzler, Sanghee Park, Rick H. Williams, Arny A. Ferrando, Nicolaas E. P. Deutz, Robert R. Wolfe, Robert H. Coker
    International Journal of Circumpolar Health.2021;[Epub]     CrossRef
  • 45. Effect of CCL11 on In Vitro Myogenesis and Its Clinical Relevance for Sarcopenia in Older Adults
    Da Ae Kim, So Jeong Park, Jin Young Lee, Jeoung Hee Kim, Seungjoo Lee, Eunju Lee, Il-Young Jang, Hee-Won Jung, Jin Hoon Park, Beom-Jun Kim
    Endocrinology and Metabolism.2021; 36(2): 455.     CrossRef
  • 46. Global prevalence of sarcopenic obesity in older adults: A systematic review and meta-analysis
    Qianqian Gao, Fan Mei, Yi Shang, Kaiyan Hu, Fei Chen, Li Zhao, Bin Ma
    Clinical Nutrition.2021; 40(7): 4633.     CrossRef
  • 47. Association of Body Composition and Sarcopenia with NASH in Obese Patients
    Sophia Marie-Therese Schmitz, Lena Schooren, Andreas Kroh, Alexander Koch, Christine Stier, Ulf Peter Neumann, Tom Florian Ulmer, Patrick Hamid Alizai
    Journal of Clinical Medicine.2021; 10(15): 3445.     CrossRef
  • 48. Sarcopenia, Obesity, and Sarcopenic Obesity: Relationship with Skeletal Muscle Phenotypes and Single Nucleotide Polymorphisms
    Praval Khanal, Alun G. Williams, Lingxiao He, Georgina K. Stebbings, Gladys L. Onambele-Pearson, Martine Thomis, Hans Degens, Christopher I. Morse
    Journal of Clinical Medicine.2021; 10(21): 4933.     CrossRef
  • 49. Associated Factors of Sarcopenia in Community-Dwelling Older Adults: A Systematic Review and Meta-Analysis
    Qianqian Gao, Kaiyan Hu, Chunjuan Yan, Bing Zhao, Fan Mei, Fei Chen, Li Zhao, Yi Shang, Yuxia Ma, Bin Ma
    Nutrients.2021; 13(12): 4291.     CrossRef
  • 50. Yaşlılarda Sarkopenik Obezite ve Güncel Beslenme Önerileri
    Büşra ÇOLAK, Seda ÇİFTÇİ
    Bandırma Onyedi Eylül Üniversitesi Sağlık Bilimleri ve Araştırmaları Dergisi.2021; 3(3): 208.     CrossRef
  • 51. The Association Between Diabetes Mellitus and Risk of Sarcopenia: Accumulated Evidences From Observational Studies
    Yu-Shun Qiao, Yin-He Chai, Hong-Jian Gong, Zhiyessova Zhuldyz, Coen D. A. Stehouwer, Jian-Bo Zhou, Rafael Simó
    Frontiers in Endocrinology.2021;[Epub]     CrossRef
  • 52. Health Consequences of Sarcopenic Obesity: A Narrative Review
    Eun Roh, Kyung Mook Choi
    Frontiers in Endocrinology.2020;[Epub]     CrossRef
  • 53. Type 2 Diabetes Mellitus is Associated with Increased Risk of Sarcopenia: A Systematic Review and Meta-analysis
    Panagiotis Anagnostis, Nifon K. Gkekas, Charoula Achilla, Georgia Papanastasiou, Polyxeni Taouxidou, Maria Mitsiou, Eustathios Kenanidis, Michael Potoupnis, Eleftherios Tsiridis, Dimitrios G. Goulis
    Calcified Tissue International.2020; 107(5): 453.     CrossRef
  • 54. New hypoglycaemic therapy in frail older people with diabetes mellitus-phenotypic status likely to be more important than functional status
    A.H. Abdelhafiz, D. Emmerton, A.J. Sinclair
    Diabetes Research and Clinical Practice.2020; 169: 108438.     CrossRef
  • 55. Sex differences in the prevalence and adverse outcomes of sarcopenia and sarcopenic obesity in community dwelling elderly in East China using the AWGS criteria
    Yanping Du, Xiaodong Wang, Hua Xie, Songbai Zheng, Xiaoqing Wu, Xiaoying Zhu, Xuemei Zhang, Sihong Xue, Huilin Li, Wei Hong, Wenjing Tang, Minmin Chen, Qun Cheng, Jianqin Sun
    BMC Endocrine Disorders.2019;[Epub]     CrossRef
  • 56. Association of lifestyle factors and inflammation with sarcopenic obesity: data from the PREDIMED‐Plus trial
    Itziar Abete, Jadwiga Konieczna, M. Angeles Zulet, Aina M. Galmés‐Panades, Idoia Ibero‐Baraibar, Nancy Babio, Ramón Estruch, Josep Vidal, Estefanía Toledo, Cristina Razquin, Rafael Bartolomé, Andrés Díaz‐Lopez, Miquel Fiol, Rosa Casas, Josep Vera, Pilar B
    Journal of Cachexia, Sarcopenia and Muscle.2019; 10(5): 974.     CrossRef
  • 57. Application of body composition zones in boys with nonalcoholic fatty liver disease
    Minhye Choi, Seonhwa Lee, Sun Hwan Bae, Sochung Chung
    Annals of Pediatric Endocrinology & Metabolism.2019; 24(4): 243.     CrossRef
  • 58. Association between sarcopenia and diabetes: a systematic review and meta-analysis of observational studies
    Nicola Veronese, Damiano Pizzol, Jacopo Demurtas, Pinar Soysal, Lee Smith, Cornel Sieber, Timo Strandberg, Isabelle Bourdel-Marchasson, Alan Sinclair, Mirko Petrovic, Stefania Maggi
    European Geriatric Medicine.2019; 10(5): 685.     CrossRef
  • 5,524 View
  • 71 Download
  • Crossref
Relationship between Bone Density, Eating Habit, and Nutritional Intake in College Students
Hee-Sook Lim, Sung-In Ji, Hyeonji Hwang, Jeongmmok Kang, Yoon-Hyung Park, Hae-Hyeog Lee, Tae-Hee Kim
J Bone Metab 2018;25(3):181-186.
Published online August 31, 2018
DOI: https://doi.org/10.11005/jbm.2018.25.3.181
Background

The importance of bone health is emphasized throughout the life cycle. Young adults have problems with bone health due to irregular lifestyle and unbalanced diet, but studies related to them are insufficient. The purpose of this study was to measure the bone mineral density (BMD) of college students and to analyze the differences in BMD according to lifestyle.

Methods

BMD was measured by bone ultrasound in 161 male and female college students. The questionnaire was surveyed about lifestyle, eating habits, and nutrient intake status.

Results

Osteopenia was 8.8% in male and 10.8% in female. The body fat percentage of female was significantly higher than male. Male college students, smoking, fast food consumption, and overeating rate were significantly higher than female. Nutrient intake was not significantly different between male and female students. But energy and vitamin A and C levels were inadequate, and protein and sodium intake was excessive compared with the recommended nutrient intake for Koreans. BMD was significantly lowest in male who often intake fast food than male who did not intake at all or intake sometimes. Female who often intake fast food had significantly lower BMD than female who did not eat at all.

Conclusions

College students have different BMDs according to lifestyle. There was a difference in BMD according to smoking and fast food consumption.

Citations

Citations to this article as recorded by  Crossref logo
  • 1. Ultra-Processed Food and Its Impact on Bone Health and Joint Diseases: A Scoping Review
    Jacopo Ciaffi, Luana Mancarella, Claudio Ripamonti, Andrea D’Amuri, Veronica Brusi, Federica Pignatti, Lucia Lisi, Francesco Ursini
    Nutrients.2025; 17(7): 1188.     CrossRef
  • 2. Assessing Bone Mineral Density Among Female Medical Students Of Pakistan: Unveiling The Impact Of Lifestyle Factors On Skeletal Health- An Analytical Cross-Sectional Study
    Afifa Kulsoom, Mehreen Noor, Eeman Naeem, Khola Noreen, Muhammad Umar Mansoor, Tahir Mahmood
    Journal of Rawalpindi Medical College.2025;[Epub]     CrossRef
  • 3. Effect of COVID‐19 pandemic on lifestyle and bone mineral density in young adults
    Darina Falbová, Viktória Kovalčíková, Radoslav Beňuš, Simona Sulis, Lenka Vorobeľová
    American Journal of Human Biology.2024;[Epub]     CrossRef
  • 4. Effects of Korean Versus Western Diets on Reproductive Function in Young Korean Men: A 12-Week Randomized Parallel Clinical Trial
    Su-Jin Jung, Young-Gon Kim, Seung-Ok Lee, Soo-Wan Chae
    Journal of Lifestyle Medicine.2024; 14(1): 20.     CrossRef
  • 5. Dietary interventions for better management of osteoporosis: An overview
    Danjun Guo, Mengge Zhao, Wei Xu, Hui He, Bin Li, Tao Hou
    Critical Reviews in Food Science and Nutrition.2023; 63(1): 125.     CrossRef
  • 6. Lifestyle and dietary changes related to weight gain in college students during the COVID-19 pandemic
    Jihyun Kim, Seunghee Kye
    Journal of Nutrition and Health.2023; 56(3): 288.     CrossRef
  • 7. Dietary guidelines adherence and changes in eating habits among college students in the post-COVID-19 period: a cross-sectional study
    Eunyoung Yoon
    Korean Journal of Community Nutrition.2023; 28(3): 220.     CrossRef
  • 8. Associations of adolescents’ diet and meal patterns with school performance in the Northern Finland Birth Cohort 1986: A Mendelian randomisation study
    Loukas Zagkos, Fotios Drenos, Pauline Emmett, Alexandra I. Blakemore, Tanja Nordström, Tuula Hurtig, Marjo-Riitta Jarvelin, Terence M. Dovey
    Appetite.2023; 190: 107036.     CrossRef
  • 9. Association of Night Eating Habits with Health-Related Quality of Life (HRQoL) in University Students
    Yoonji Kim, Jung Hyun Kwak, Jean Kyung Paik
    Healthcare.2022; 10(4): 640.     CrossRef
  • 10. Effect of Difference in Dietary Behavior and Lifestyle by Nutrition Knowledge Level Among College Students in Pyeongtaek Area
    Seo Hyeon Ahn, Seong Yeong Kim
    Korean Journal of Human Ecology.2022; 31(2): 249.     CrossRef
  • 11. High prevalence of low dairy calcium intake and association with insomnia, anxiety, depression and musculoskeletal pain in university students from Jordan
    Mohammad J Alkhatatbeh, Hala N Khwaileh, Khalid K Abdul-Razzak
    Public Health Nutrition.2021; 24(7): 1778.     CrossRef
  • 12. Change of dietary habits and the use of home meal replacement and delivered foods due to COVID-19 among college students in Chungcheong province, Korea
    Mi-Hyun Kim, Jee-Young Yeon
    Journal of Nutrition and Health.2021; 54(4): 383.     CrossRef
  • 13. Nutrition Knowledge and Eating Behaviors among College Students in the Pyeongtaek Area
    Seo Hyeon Ahn, Seong Yeong Kim
    Journal of the East Asian Society of Dietary Life.2020; 30(3): 235.     CrossRef
  • 14. Comparative Study of Eating Habits and Lifestyle by Gender among College Students in Pyeongtaek Region
    Seo Hyeon Ahn, Seong Yeong Kim
    Journal of the East Asian Society of Dietary Life.2020; 30(2): 117.     CrossRef
  • 15. Bone Mineral Density in Adolescent Boys: Cross-Sectional Observational Study
    Anna Kopiczko, Jakub Grzegorz Adamczyk, Monika Łopuszańska-Dawid
    International Journal of Environmental Research and Public Health.2020; 18(1): 245.     CrossRef
  • 16. Frequency of Osteopenia and its association with dietary factors among female population aged 18-60 years
    Sana Zahid, Asif Hanif, Tallat Anwar Faridi, Zahid Masood, Akash John
    DIET FACTOR (Journal of Nutritional & Food Sciences).2020; : 48.     CrossRef
  • 17. Associations between Dietary Fiber Intake and Bone Mineral Density in Adult Korean Population: Analysis of National Health and Nutrition Examination Survey in 2011
    Taehoon Lee, Heuy Sun Suh
    Journal of Bone Metabolism.2019; 26(3): 151.     CrossRef
  • 5,430 View
  • 52 Download
  • Crossref
Serum Vitamin D Level Related to Coffee Consumption in Korean Young Adults Using the 5th Korea National Health and Nutrition Examination Survey
Hee-Sook Lim, Hae-Hyeog Lee, Dong-Won Byun, Bora Lee, Temuulee Enkhbold, Tae-Hee Kim
J Bone Metab 2017;24(4):229-233.
Published online November 30, 2017
DOI: https://doi.org/10.11005/jbm.2017.24.4.229
Background

Even young adults are highly interested in their osteological health, yet their calcium intake does not match the level of such interest. Increase in bone loss is known to be associated with higher intake of caffeine and coffee consumption among the young Korean is rising steadily. This study was conducted to reveal the relationship between coffee consumption and serum vitamin D level in Korean young adults.

Methods

This study analyzed potential difference in lifestyle and concentration of vitamin D in blood in relation to coffee intake frequency of 2,523 subjects on the basis of data from the 5th Korea National Health and Nutrition Examination Survey.

Results

According to the analysis, groups of males, with high income, frequent social activity followed by alcohol consumption and smoking, and high rate of dining out showed a high frequency of coffee consumption. Vitamin D concentration among the groups was 16.2±5.3 mL and 80.3% of them were considered to be vitamin D-deficient. All the groups appeared to have deficiencies compared to males who did not consume caffeine at all.

Conclusions

The practice of having an adequate amount of coffee is needed, and more efforts should be done to improve vitamin D intake among young adults.

Citations

Citations to this article as recorded by  Crossref logo
  • 1. Coffee consumption and its association with vitamin D level, lifestyle factors, and mental health symptoms among adults in Saudi Arabia
    Noor A. Hakim
    The Journal of Steroid Biochemistry and Molecular Biology.2026; 257: 106923.     CrossRef
  • 2. Prevalence and determinants of vitamin D deficiency among pregnant women in Gondar Town 2024: a cross-sectional study from the first and second trimesters
    Elias Chane, Bisrat Birke Teketelew, Dereje Mengesha Berta, Muluken Walle, Abiy Ayele Angelo, Negesse Cherie, Mebratu Tamir, Zufan Yiheyis Abriham, Getachew Bitew, Amare Mekuanint
    BMJ Open.2025; 15(10): e101092.     CrossRef
  • 3. Effect of air temperature on serum 25-hydroxyvitamin D concentrations: A single institutional large-scale study in Korea
    Kyung Hee Han, Yujin Jeong, Young Ju Suh, Dong Hoon Suh, Kidong Kim, Yong Beom Kim, Jae Hong No, Dong Keon Yon
    PLOS ONE.2024; 19(3): e0297495.     CrossRef
  • 4. The association of coffee consumption rate with serum 25-hydroxyvitamin D, non-HDL levels, and TC/HDL ratio in females with vitamin D deficiency
    Maha Habash, Sami Al-shakhshir, Mohammad Abusamak, Mohammad Yasin Mohammad, Mahmoud AbuSamak
    Women's Health.2022;[Epub]     CrossRef
  • 5. Analysis of risk factors for vitamin D deficiency by results of the first stage of Russian non-interventional register study
    L. A. Suplotova, V. A. Avdeeva, L. Y. Rozhinskaya, E. A. Pigarova, E. A. Troshina
    Meditsinskiy sovet = Medical Council.2021; (7): 109.     CrossRef
  • 5,172 View
  • 16 Download
  • Crossref
Relationship between Serum 25-hydroxy-vitamin D Concentration and Risk of Metabolic Syndrome in Patients with Fatty Liver
Hee-Sook Lim, Tae-Hee Kim, Hae-Hyeog Lee, Soon-Kyung Kim, Bora Lee, Yoon-Hyung Park
J Bone Metab 2017;24(4):223-228.
Published online November 30, 2017
DOI: https://doi.org/10.11005/jbm.2017.24.4.223
Background

The vitamin D deficiency rate in Koreans is still high and dietary intake is insufficient. The purpose of this study was to provide basic data for the management of metabolic syndrome (MetS) by analyzing the effect of vitamin D levels on the MetS in patients with fatty liver.

Methods

We analyzed the MetS ratio and serum 25-hydroxy-vitamin D (25[OH]D) concentration in 151 adults diagnosed with fatty liver by using obesity index and blood profiles. We collected data on demographic factors, nutrient intake, and lifestyle habits.

Results

The mean 25(OH)D concentration of all subjects was 14 ng/mL and the insufficiency and deficiency rates were 40.4% and 29.8%. The proportion of MetS was 38.4% and the mean 25(OH)D level of MetS group was 12.1 ng/mL. Low-density lipoprotein cholesterol, triglyceride, and blood glucose were higher in the MetS group than in the normal group, and the waist circumference of the male was significantly higher than that of the normal group. The results showed that the lower the vitamin D concentration, the higher the risk of MetS (odds ratio, 1.47, 95% confidence interval, 0.98–2.81; P=0.043).

Conclusions

These results suggest that serum 25(OH)D levels may be a risk factor for MetS in patients with fatty liver.

Citations

Citations to this article as recorded by  Crossref logo
  • 1. Vitamin D Status Presents Different Relationships with Severity in Metabolic-Associated Fatty Liver Disease Patients with or without Hepatitis B Infection
    Ling Luo, Junzhao Ye, Congxiang Shao, Yansong Lin, Yanhong Sun, Shiting Feng, Wei Wang, Bihui Zhong
    Nutrients.2022; 14(10): 2114.     CrossRef
  • 2. Serum vitamin D levels in relation to metabolic syndrome: A systematic review and dose–response meta‐analysis of epidemiologic studies
    Zahra Hajhashemy, Farnaz Shahdadian, Elham Moslemi, Fateme Sadat Mirenayat, Parvane Saneei
    Obesity Reviews.2021;[Epub]     CrossRef
  • 3. Vitamin D and the Immune System. When? Why? How?
    Alida Moise, Carmen Balescu-Arion
    Central European Annals of Clinical Research.2020; 2(1): 1.     CrossRef
  • 4. Is There a Difference in Serum Vitamin D Levels and Bone Mineral Density According to Body Mass Index in Young Adult Women?
    Hee-Sook Lim, Dong Won Byun, Kyo Il Suh, Hyeong Kyu Park, Hye Jeong Kim, Tae-Hee Kim, Hae-Hyeog Lee
    Journal of Bone Metabolism.2019; 26(3): 145.     CrossRef
  • 5. Regulation of Microbiota by Vitamin D Receptor: A Nuclear Weapon in Metabolic Diseases
    Danika Bakke, Ishita Chatterjee, Annika Agrawal, Yang Dai, Jun Sun
    Nuclear Receptor Research.2018;[Epub]     CrossRef
  • 6. Nutraceutical Approach to Non-Alcoholic Fatty Liver Disease (NAFLD): The Available Clinical Evidence
    Arrigo F. G. Cicero, Alessandro Colletti, Stefano Bellentani
    Nutrients.2018; 10(9): 1153.     CrossRef
  • 7. Hepatitis B virus downregulates vitamin D receptor levels in hepatoma cell lines, thereby preventing vitamin D-dependent inhibition of viral transcription and production
    Neta Gotlieb, Irena Tachlytski, Yelena Lapidot, Maya Sultan, Michal Safran, Ziv Ben-Ari
    Molecular Medicine.2018;[Epub]     CrossRef
  • 8. Impact of Western and Mediterranean Diets and Vitamin D on Muscle Fibers of Sedentary Rats
    Francesca Maria Trovato, Paola Castrogiovanni, Marta Anna Szychlinska, Francesco Purrello, Giuseppe Musumeci
    Nutrients.2018; 10(2): 231.     CrossRef
  • 4,877 View
  • 56 Download
  • Crossref
Relationship between Heavy Metal Exposure and Bone Mineral Density in Korean Adult
Hee-Sook Lim, Hae-Hyeog Lee, Tae-Hee Kim, Bo-Ra Lee
J Bone Metab 2016;23(4):223-231.
Published online November 30, 2016
DOI: https://doi.org/10.11005/jbm.2016.23.4.223
Background

Exposure to heavy metals from environmental and industrial sources remains a concern of serious public health risk. This study was conducted to analysis the relationship between heavy metal concentrations and bone density.

Methods

This study used data from a nation-based sample of Koreans (n=2,429) from 2008 to 2011 Korea National Health and Nutrition Examination Survey. We were obtained heavy metals (lead, mercury and cadmium), socioeconomic and demographic factors and bone mineral density (BMD) measured by T-score.

Results

Menopausal women, current smoker or the frequent alcohol drinking, low educational level and low family income were greater in the osteopenia or osteoporosis groups than normal group, and were associated with an increased blood heavy metal concentration levels. The highest quartile group in blood lead had a 1.47 times (95% confidence interval [CI] 1.16-1.87) risk of osteopenia or osteoporosis. In case of blood cadmium, the risk for osteopenia or osteoporosis increased 2.1 times (95% CI 1.64-2.68).

Conclusions

We observed a significant association between blood heavy metals (lead and cadmium) levels and low BMD. Our findings suggest that heavy metal exposure may be a risk factor for osteoporosis.

Citations

Citations to this article as recorded by  Crossref logo
  • 1. Association of urinary heavy metals with osteoporosis in US adults using interpretable machine learning
    Weihuan Huang, Dongpei Liu, Gang Liu, Guihua Chen
    Toxicology Letters.2026; 417: 111853.     CrossRef
  • 2. AMP1-1 derived from Atractylodes macrocephala Koidz prevents bone aging triggered by lead and cadmium
    Jinpeng Wang, Yu Jiang, Xiaoyu Hou, Tahir Raza, Yiping He, Xinyue Liu, Defeng Xing, Lijun Wei
    Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology.2025; 294: 110189.     CrossRef
  • 3. Impact of Maternal Exposure to Trace Metal Mixtures on Bone Mineral Density in Children Aged 3–6: Results from the Guangxi Zhuang Birth Cohort, China
    Junwang Gu, Huishen Huang, Jun Liang, Qian Liao, Peng Tang, Ying Tang, Jinghua Long, Jiehua Chen, Dongping Huang, Dongxiang Pan, Xiaoyun Zeng, Xiaoqiang Qiu
    Biological Trace Element Research.2025; 203(10): 5068.     CrossRef
  • 4. The impact of heavy metals on osteoporosis in postmenopausal women
    Shiyu Peng, Gaoxiang Zhang, Decheng Wang, Zhiliang He
    Frontiers in Environmental Health.2025;[Epub]     CrossRef
  • 5. Osteoclast-derived exosomal miR-30a-3p promotes lead exposure-induced osteoporosis by triggering osteoblastic pyroptosis
    Yue Gao, Hang Zhang, Yinnong Jia, Yuanfang Chen, Luna Wang, Jie Ding, Wen Wang, Baoli Zhu, Liu Ouyang, Xu He, Yan An, Tingting Yu, Hengdong Zhang, Ming Xu
    Clinical Science.2025; 139(07): 389.     CrossRef
  • 6. Metal(oid) profiling of the common site of osteoporotic fractures with bone microarchitecture correlation analysis: a comparative study of hip fracture patients and healthy individuals
    Aleksandar Cirovic, Danijela Djonic, Vladimir Zivkovic, Slobodan Nikolic, Marija Djuric, Petar Milovanovic
    BioMetals.2025; 38(3): 965.     CrossRef
  • 7. Approach to premenopausal osteoporosis
    Khushboo Agarwal, Lakshmi Nagendra, Saptarshi Bhattacharya
    Current Opinion in Endocrinology, Diabetes & Obesity.2025; 32(6): 251.     CrossRef
  • 8. Disentangling the Relationship Between Urinary Metal Exposure and Osteoporosis Risk Across a Broad Population: A Comprehensive Supervised and Unsupervised Analysis
    Jianing Liu, Kai Wang
    Toxics.2024; 12(12): 866.     CrossRef
  • 9. Associations Between Exposure to Metal Mixtures and Insufficient Bone Strength: A Cross-Sectional Study Among Children Aged 2–6 Years
    Yanli Liu, Yan Wang, Ye Fu, Yang Liu, Mingzhu Li, Minghui He, Yao Zhang, Chen Li, Hongcheng Ding, Xiaowen Li, Hongxian Ji, Jing Wang
    Exposure and Health.2024; 16(3): 791.     CrossRef
  • 10. Association Between Combined Polymetallic Exposure and Osteoporosis
    Lidong Qin, Qiumei Liu, Tiantian Zhang, Xu Tang, Xiaoting Mo, Yujian Liang, Xuexiu Wang, Jiejing Cao, Chuwu Huang, Yufu Lu, Zhiyong Zhang, Jian Qin, Jiansheng Cai
    Biological Trace Element Research.2024; 202(9): 3945.     CrossRef
  • 11. Metals accumulation affects bone and muscle in osteoporotic patients: A pilot study
    Beatrice Battistini, Chiara Greggi, Virginia Veronica Visconti, Marco Albanese, Alessandra Messina, Patrizia De Filippis, Beatrice Gasperini, Angela Falvino, Prisco Piscitelli, Leonardo Palombi, Umberto Tarantino
    Environmental Research.2024; 250: 118514.     CrossRef
  • 12. Association Between Multiple Heavy Metal Exposures and Cholesterol Levels in Residents Living Near a Smelter Plant in Korea
    Sun-In Moon, Dong-Hyuk Yim, Kyunghi Choi, Sang-Yong Eom, Byung-Sun Choi, Jung-Duck Park, Heon Kim, Yong-Dae Kim
    Journal of Korean Medical Science.2024;[Epub]     CrossRef
  • 13. Mitigating lead-induced osteoporosis: The role of butyrate in gut-bone axis restoration
    Yuqiu Ge, Zhongtang Jia, Shiting Zhao, WenChao Zhang, Xian Shi, Ruijin Xie, Yan Gong, Jixiang Sheng, Rob J. van 't Hof, Jiatao Yang, Chunqing Han, Xiping Hu, Yafeng Wang, Yu Wu, Chunping Li, Miaomiao Wang
    Ecotoxicology and Environmental Safety.2024; 283: 116943.     CrossRef
  • 14. The influence of adult urine lead exposure on bone mineral densit: NHANES 2015-2018
    Shaokang Wang, Xiaofeng Zhao, Runtian Zhou, Yuanzhang Jin, Xiaonan Wang, Xiaotian Ma, Xiangdong Lu
    Frontiers in Endocrinology.2024;[Epub]     CrossRef
  • 15. Association of per- and polyfluoroalkylated substances/heavy metals and bone health in children and adolescents
    Yumeng Wei, Yuxiao Zhang, Qiaoyun Ji, Sufei Yang, Fan Yang
    Frontiers in Public Health.2024;[Epub]     CrossRef
  • 16. Relationship of multiple metals mixture and osteoporosis in older Chinese women: An aging and longevity study
    Xiuming Feng, Gaohui Zan, Yue Wei, Xiaoting Ge, Haiqing Cai, Tianzhu Long, Lianguang Xie, Lei Tong, Chaoqun Liu, Longman Li, Lulu Huang, Fei Wang, Xing Chen, Haiying Zhang, Yunfeng Zou, Zhiyong Zhang, Xiaobo Yang
    Environmental Pollution.2023; 317: 120699.     CrossRef
  • 17. Fingerprinting of heavy metal and microbial contamination uncovers the unprecedented scale of water pollution and its implication on human health around transboundary Hudiara drain in South Asia
    Zainab Nasir, Ambreen Sabir, Hafiz Muhammad Salman, Muhammad Usman Ashraf, Muhammad Farhan Khalid, Muhammad Burhan Khalid, Zonaira Khalid, Amna Tahir, Fatima Arshad, Hafiz Gohar Ejaz, Saneela Ashraf, Sheikha Hina Liaqat, Huma Khawar, Risham Hussain, Muham
    Environmental Technology & Innovation.2023; 30: 103040.     CrossRef
  • 18. Risk of Environmental Chemicals on Bone Fractures Is Independent of Low Bone Mass in US Adults: Insights from 2017 to 2018 NHANES
    Run Ling, Yuanli Ai, Chengzhi Chen, Jun Zhang, Zhen Zou, Shuqun Cheng, Chunli Li, Xi Li, Bin Wang
    Metabolites.2023; 13(3): 346.     CrossRef
  • 19. Relationship of blood heavy metals and osteoporosis among the middle-aged and elderly adults: A secondary analysis from NHANES 2013 to 2014 and 2017 to 2018
    Zengfa Huang, Xiang Wang, Hui Wang, Shutong Zhang, Xinyu Du, Hui Wei
    Frontiers in Public Health.2023;[Epub]     CrossRef
  • 20. Association between dietary intake of α-tocopherol and cadmium related osteoporosis in population ≥ 50 years
    Renjia Li, Hai Qu, Jinwei Xu, Huiqin Yang, Jinyao Chen, Lishi Zhang, Jiuming Yan
    Journal of Bone and Mineral Metabolism.2023; 41(4): 501.     CrossRef
  • 21. Nutraceuticals as Alternative Approach against Cadmium-Induced Kidney Damage: A Narrative Review
    Herbert Ryan Marini, Federica Bellone, Antonino Catalano, Giovanni Squadrito, Antonio Micali, Domenico Puzzolo, José Freni, Giovanni Pallio, Letteria Minutoli
    Metabolites.2023; 13(6): 722.     CrossRef
  • 22. Plasma heavy metal levels correlate with deregulated gene expression of detoxifying enzymes in osteoporotic patients
    V. V. Visconti, B. Gasperini, C. Greggi, B. Battistini, A. Messina, M. Renzi, K. Bakhtafrouz, R. Iundusi, A. Botta, L. Palombi, U. Tarantino
    Scientific Reports.2023;[Epub]     CrossRef
  • 23. Study of thorium-induced micro-structural changes in mice femoral bone using SR-µCT
    Ashish K. Agrawal, Rakhee Yadav, Balwant Singh, Manjoor Ali, Amit Kumar, Yogesh Kashyap, Badri N. Pandey
    Toxicology and Environmental Health Sciences.2023; 15(4): 399.     CrossRef
  • 24. Análisis espacial de metales pesados en suelos agrícolas de la subcuenca Atoyac-Zahuapan y riesgos de salud pública.
    Numa Pompilio Castro González, Francisco Calderón Sánchez, Guillermo Jesuita Pérez Marroquín
    Agricultura, Sociedad y Desarrollo.2023;[Epub]     CrossRef
  • 25. Serum heavy metals of passive smoker females and its correlation to bone biomarkers and risk of osteoporosis
    Abeer Abdulrahman Banjabi, Kannan Kurunthachalam, Taha Abdullah Kumosani, Khalid Omar Abulnaja, Abdulrahman Labeed AL-Malki, Said Salama Moselhy
    Environmental Science and Pollution Research.2022; 29(5): 6943.     CrossRef
  • 26. Cosmetic use and serum level of lead (not cadmium) affect bone mineral density among young Iranian women
    Maryam GhaseminasabParizi, Zahra Sedaghat, Seyed Mohammad Mazloomi, Hadith Tangestani, Mesbah Shams, Mohammad Fararouei
    Environmental Science and Pollution Research.2022; 29(9): 13459.     CrossRef
  • 27. The association between hemoglobin level and osteoporosis in a Chinese population with environmental lead and cadmium exposure
    Miaomiao Wang, Xinru Wang, Wenjing Cui, Guoying Zhu, Yihuai Liang, Xiao Chen, Taiyi Jin
    Environmental Geochemistry and Health.2022; 44(6): 1673.     CrossRef
  • 28. The Association between Lead Exposure and Bone Mineral Density in Childhood and Adolescence: Results from NHANES 1999–2006 and 2011–2018
    Tao Li, Yixuan Xie, Liang Wang, Guimin Huang, Yijing Cheng, Dongqing Hou, Wenqian Liu, Tong Zhang, Junting Liu
    Nutrients.2022; 14(7): 1523.     CrossRef
  • 29. Long-Term Sex-Specific Effects of Cadmium Exposure on Osteoporosis and Bone Density: A 10-Year Community-Based Cohort Study
    Seung Min Chung
    Journal of Clinical Medicine.2022; 11(10): 2899.     CrossRef
  • 30. Blood Lead Level Is Negatively Associated With Bone Mineral Density in U.S. Children and Adolescents Aged 8-19 Years
    Aiyong Cui, Peilun Xiao, Baoliang Hu, Yuzhuo Ma, Zhiqiang Fan, Hu Wang, Fengjin Zhou, Yan Zhuang
    Frontiers in Endocrinology.2022;[Epub]     CrossRef
  • 31. Potential ecological risk assessment of heavy metals (trace elements) in coastal soils of southwest Iran
    Ebtessam Hamid, Khoshnaz Payandeh, Mohammad Tahsin Karimi Nezhad, Naghmeh Saadati
    Frontiers in Public Health.2022;[Epub]     CrossRef
  • 32. Follicle-stimulating hormone and blood lead levels with bone mineral density and the risk of fractures in pre- and postmenopausal women
    Huixin Tong, Bo Su, Zhize Liu, Yongjie Chen
    Frontiers in Endocrinology.2022;[Epub]     CrossRef
  • 33. Blood Lead Level is Negatively Associated with Bone Mineral Density in Children and Adolescents Aged 8-19 Years
    Aiyong Cui, Pei-Lun Xiao, Baoliang Hu, Yuzhuo Ma, Zhiqiang Fan, Hu Wang, Fengjin Zhou, Yan Zhuang
    SSRN Electronic Journal .2022;[Epub]     CrossRef
  • 34. Evaluation of Cadmium Chloride-Induced Toxicity in Chicks Via Hematological, Biochemical Parameters, and Cadmium Level in Tissues
    Shaukat Ali, Saleha Bashir, Shumaila Mumtaz, Hafiz Abdullah Shakir, Chaman Ara, Farooq Ahmad, Hafiz Muhammad Tahir, Mehwish Faheem, Muhammad Irfan, Azeem Masih, Mazhar Ulhaq, Saiqa Andleeb
    Biological Trace Element Research.2021; 199(9): 3457.     CrossRef
  • 35. Evaluation of La(XT), a novel lanthanide compound, in an OVX rat model of osteoporosis
    Yunyun Di, Ellen K. Wasan, Jacqueline Cawthray, Jaweria Syeda, Munawar Ali, David M.L. Cooper, Ahmad Al-Dissi, Nima Ashjaee, Wubin Cheng, James Johnston, David M. Weekes, Thomas I. Kostelnik, Chris Orvig, Kishor M. Wasan
    Bone Reports.2021; 14: 100753.     CrossRef
  • 36. Metal exposure and bone remodeling during pregnancy: results from the PROGRESS cohort study
    Citlalli Osorio-Yáñez, Marco Sanchez-Guerra, Maritsa Solano, Andrea Bacarelli, Robert Wright, Alison P. Sanders, Martha Maria Tellez-Rojo, Marcela Tamayo-Ortiz
    Environmental Pollution.2021; : 116962.     CrossRef
  • 37. Urine Cadmium as a Risk Factor for Osteoporosis and Osteopenia: A Meta-Analysis
    Dong Li, HaoJie Lin, Min Zhang, Jing Meng, LiYou Hu, Bo Yu
    Frontiers in Medicine.2021;[Epub]     CrossRef
  • 38. STANDARDIZED EXPERIMENTAL MODEL FOR CEMENT DUST EXPOSURE; TISSUE HEAVY METAL BIOACCUMULATION AND PULMONARY PATHOLOGICAL CHANGES IN RATS
    M.W. Owonikoko, B.O. Emikpe, S.B. Olaleye
    Toxicology Reports.2021;[Epub]     CrossRef
  • 39. Associations of multiple metals with bone mineral density: A population-based study in US adults
    Mu-hong Wei, Yuan Cui, Hao-long Zhou, Wen-jing Song, Dong-sheng Di, Ru-yi Zhang, Qin Huang, Jun-an Liu, Qi Wang
    Chemosphere.2021; 282: 131150.     CrossRef
  • 40. Blood lead and cadmium levels are negatively associated with bone mineral density in young female adults
    Jianfeng Lu, Ji Lan, Xiao’e Li, Zhongxin Zhu
    Archives of Public Health.2021;[Epub]     CrossRef
  • 41. Alcohol Consumption Moderated the Association Between Levels of High Blood Lead or Total Urinary Arsenic and Bone Loss
    Yu-Mei Hsueh, Ya-Li Huang, Hsi-Hsien Chen, Horng-Sheng Shiue, Ying-Chin Lin, Ru-Lan Hsieh
    Frontiers in Endocrinology.2021;[Epub]     CrossRef
  • 42. Nigerian foods of probiotics relevance and chronic metal exposure: a systematic review
    Orish Ebere Orisakwe, Cecilia Nwadiuto Amadi, Chiara Frazzoli, Awolayeofori Dokubo
    Environmental Science and Pollution Research.2020; 27(16): 19285.     CrossRef
  • 43. Exposure to heavy metals and the risk of osteopenia or osteoporosis: a systematic review and meta-analysis
    C. Jalili, M. Kazemi, E. Taheri, H. Mohammadi, B. Boozari, A. Hadi, S. Moradi
    Osteoporosis International.2020; 31(9): 1671.     CrossRef
  • 44. The associations among lead exposure, bone mineral density, and FRAX score: NHANES, 2013 to 2014
    Wei-Jie Wang, Chang-Chin Wu, Wei-Ting Jung, Chien-Yu Lin
    Bone.2019; 128: 115045.     CrossRef
  • 45. Heavy metal exposure has adverse effects on the growth and development of preschool children
    Xiang Zeng, Xijin Xu, Qilin Qin, Kai Ye, Weidong Wu, Xia Huo
    Environmental Geochemistry and Health.2019; 41(1): 309.     CrossRef
  • 46. The association between body lead levels and childhood rickets
    Yong-fang Zhang, Jiang-wei Xu, Yao Yang, Xueqin Huang, Xin-qiao Yu
    Medicine.2019; 98(8): e14680.     CrossRef
  • 47. Chronic arsenicosis and cadmium exposure in wild snowshoe hares (Lepus americanus) breeding near Yellowknife, Northwest Territories (Canada), part 2: Manifestation of bone abnormalities and osteoporosis
    S. Amuno, A. Al Kaissi, A. Jamwal, S. Niyogi, C.E. Quenneville
    Science of The Total Environment.2018; 612: 1559.     CrossRef
  • 48. Avaliação dos níveis de chumbo e mercúrio em população exposta ambientalmente na Região Centro-oeste do Brasil
    Leda Diva Freitas de Jesus, Maria de Fátima Ramos Moreira, Sayonara Vieira de Azevedo, Renato Marçullo Borges, Regina Aderne de Almeida Gomes, Fernanda Pereira Baptista Bergamini, Liliane Reis Teixeira
    Cadernos de Saúde Pública.2018;[Epub]     CrossRef
  • 49. White Tea is More Effective in Preservation of Bone Loss in Adult Rats Co-Exposed to Lead and Cadmium Compared to Black, Red or Green Tea
    Ewa Tomaszewska, Siemowit Muszyński, Piotr Dobrowolski, Anna Winiarska-Mieczan, Małgorzata Kwiecień, Agnieszka Tomczyk-Warunek, Marta Ejtel, Izabela Świetlicka, Bożena Gładyszewska
    Annals of Animal Science.2018; 18(4): 937.     CrossRef
  • 50. Dietary Intake of Cadmium, Lead and Mercury and Its Association with Bone Health in Healthy Premenopausal Women
    Jesus Lavado-García, Luis Puerto-Parejo, Raul Roncero-Martín, Jose Moran, Juan Pedrera-Zamorano, Ignacio Aliaga, Olga Leal-Hernández, Maria Canal-Macias
    International Journal of Environmental Research and Public Health.2017; 14(12): 1437.     CrossRef
  • 5,154 View
  • 38 Download
  • Crossref
Comparison in Adherence to Osteoporosis Guidelines according to Bone Health Status in Korean Adult
Hee-Sook Lim, Soon-Kyung Kim, Hae-Hyeog Lee, Dong Won Byun, Yoon-Hyung Park, Tae-Hee Kim
J Bone Metab 2016;23(3):143-148.
Published online August 31, 2016
DOI: https://doi.org/10.11005/jbm.2016.23.3.143
Background

Osteoporosis one of the most serious disease to decrease the quality of life and cause economic loss. Thus, prevention of osteoporosis has become an important health concern. The study examined in adherence to osteoporosis guidelines and compared the levels of adherence to osteoporosis guidelines between bone health status in Korean adult.

Methods

This study used data from a nationally represented sample of Koreans (n=3,419) from 2008 to 2011 Korea National Health and Nutrition Examination Survey. We were divided into three groups by T-score: normal, osteopenia and osteoporosis. Assessment of adherence level was based on 5 components of osteoporosis guidelines, considering intake of sodium, calcium and protein, smoking and regular exercise.

Results

The sex, body mass index, income and educational level did not significantly differ between three groups. Deficient intake of calcium was significantly associated with a threefold greater odds in osteoporosis group (OR 3.6; 95% confidence interval [CI] 2.52-5.22). Excessive protein intake was significantly increased the risk only in osteoporosis group compared to the normal group (OR 1.71; 95% CI 1.15-2.62). Smoking increased the risk in osteoporosis group compared to the normal group (OR 2.88; 95% CI 1.75-4.76), osteoporosis group compared to the osteopenia group (OR 2.69; 95% CI 1.61-4.55).

Conclusions

Nutritional factor (intake of calcium and protein) and lifestyle-related factor (smoking and exercise) must be accompanied the management for bone health. An adherence of guidelines is considered very important for the prevention of osteoporosis.

Citations

Citations to this article as recorded by  Crossref logo
  • 1. Liu-type shrinkage estimators for mixture of logistic regressions: an osteoporosis study
    Elsayed Ghanem, Armin Hatefi, Hamid Usefi
    Communications in Statistics - Simulation and Computation.2025; 54(12): 5180.     CrossRef
  • 2. Multiple observers ranked set samples for shrinkage estimators
    Andrew David Pearce, Armin Hatefi
    Journal of Applied Statistics.2024; 51(14): 2779.     CrossRef
  • 3. Unsupervised Liu-type shrinkage estimators for mixture of regression models
    Elsayed Ghanem, Armin Hatefi, Hamid Usefi
    Statistical Methods in Medical Research.2024; 33(8): 1376.     CrossRef
  • 4. Efficient estimators with categorical ranked set samples: estimation procedures for osteoporosis
    Armin Hatefi, Amirhossein Alvandi
    Journal of Applied Statistics.2022; 49(4): 803.     CrossRef
  • 5. A Research on the Incidence of Risk Factors of Osteoporosis in Women
    Melda Kangalgil, Eren Canbolat, Funda Pınar Çakıroğlu
    Ankara Medical Journal.2018;[Epub]     CrossRef
  • 6. The Factors Influencing the Bone Mineral Density in Korean Adult Men : Based on Korea National Health and Nutrition Examination Survey 2010~2011 Data
    Hye-Sang Lee
    Korean Journal of Community Nutrition.2017; 22(2): 136.     CrossRef
  • 7. Relationship between Heavy Metal Exposure and Bone Mineral Density in Korean Adult
    Hee-Sook Lim, Hae-Hyeog Lee, Tae-Hee Kim, Bo-Ra Lee
    Journal of Bone Metabolism.2016; 23(4): 223.     CrossRef
  • 4,705 View
  • 16 Download
  • Crossref
Relationship between Serum Inflammatory Marker and Bone Mineral Density in Healthy Adults
Hee-Sook Lim, Yoon-Hyung Park, Soon-Kyung Kim
J Bone Metab 2016;23(1):27-33.
Published online February 29, 2016
DOI: https://doi.org/10.11005/jbm.2016.23.1.27
Background

Inflammatory markers have been shown to play an important role in bone remodeling. The purpose of this study was to investigate the relationship among serum C-reactive protein (CRP), adiponectin, tumor necrosis factor-alpha (TNF-α) and bone health in healthy adults.

Methods

We measured serum levels of CRP, adiponectin, TNF-α as well as lumbar spine and femoral neck bone mineral density (BMD) in 76 adults. Anthropometric measurements and nutrient intake survey of participants were carried out. The participants were divided into two groups (normal BMD group=40; 52.6%, decreased BMD group=36; 47.4%).

Results

The CRP concentration was significantly higher in the decreased BMD group. The adiponectin concentration was lower in the decreased BMD group but the difference was not significant. The TNF-α concentration was higher in the decreased BMD group, the difference was not significant. The participants in the decreased BMD group were found to have lower calcium intakes. The sodium intake of the decreased BMD group was significantly higher. The BMD in the decreased BMD group showed inverse correlations with CRP and dietary sodium intake.

Conclusions

Serum CRP and dietary sodium intake is associated with BMD. Further research is needed to confirm the potential role of inflammatory marker to modulate the effects on bone.

Citations

Citations to this article as recorded by  Crossref logo
  • 1. Intra-Articular Injection of Human Bone Marrow–Derived Mesenchymal Stem Cells in Knee Osteoarthritis: A Randomized, Double-Blind, Controlled Trial
    Bong-Woo Lee, Jennifer Jooha Lee, Joon-Yong Jung, Ji Hyeon Ju
    Cell Transplantation.2025;[Epub]     CrossRef
  • 2. Evaluation of C-Reactive Protein to Albumin Ratio and Systemic Inflammation in Postmenopausal Osteoporosis
    Esra Şahingöz Bakırcı, Mustafa Bakırcı
    Genel Tıp Dergisi.2025; 35(2): 334.     CrossRef
  • 3. Interplay of Vitamin D, Inflammation, and Bone Health in Emirati Patients with Type 2 Diabetes: A Cross-sectional Study
    Hilda Allam, Hayder Hasan, Raed AbuOdeh, Jalal Taneera, Salah Abusnana, Wiam Elshami, Mohamed Abuzaid, Hussam Abusahmin, Get Bee Yvonne-Tee, Hamid Jan Jan Mohamed
    Saudi Journal of Medicine & Medical Sciences.2025; 13(4): 260.     CrossRef
  • 4. Diagnosis and Management of Legg-Calvé-Perthes Disease in the Obese Pediatric Population
    Lauren Beckish, Madison Ging, Maria Mosman, Cody Kelley, Landree Wilkin, Olivia Wills, Madison Adams, Cassidy Pinion, Cheyenne Bilica, Alavia Anderson, Margaret Sims, Michael Beckish, Deanna M. Schmitt
    JBJS Journal of Orthopaedics for Physician Assistants.2024; 12(3): e24.00013.     CrossRef
  • 5. Bone Mineral Density, Bone Biomarkers, and Joints in Acute, Post, and Long COVID-19: A Systematic Review
    Fahad Alghamdi, Kinan Mokbel, Robert Meertens, Abasiama Dick Obotiba, Mansour Alharbi, Karen M. Knapp, William David Strain
    Viruses.2024; 16(11): 1694.     CrossRef
  • 6. Plasma Trans Fatty Acids Concentrations Are Inversely Related to Bone Mineral Density and This Appears to Be Independent of Inflammation
    Mohsen Mazidi, Gordon A. Ferns
    Journal of the American Nutrition Association.2023; 42(5): 427.     CrossRef
  • 7. Leptin to adiponectin ratio in puberty is associated with bone mineral density in 18-year-old males
    Reeli Tamme, Jaak Jürimäe, Evelin Mäestu, Liina Remmel, Priit Purge, Eva Mengel, Vallo Tillmann
    Bone Reports.2022; 16: 101158.     CrossRef
  • 8. Duration of the untreated period affects bone mineral density in psychiatric patients requiring long‐term hospitalization: A cross‐sectional study
    Itsuka Kaga, Hiroyoshi Iwata, Akihiro Tokushige, Takushiro Akata, Shinichiro Ueda
    Psychiatry and Clinical Neurosciences Reports.2022;[Epub]     CrossRef
  • 9. The Relationship Between Laboratory Findings and Bone Mineral Density in Patients with Osteoporosis
    Gülseren Dost Sürücü, Dilay Eken Gedik
    Turkish Journal of Osteoporosis.2022; 28(2): 147.     CrossRef
  • 10. C-reactive protein and fracture risk: an updated systematic review and meta-analysis of cohort studies through the use of both frequentist and Bayesian approaches
    H. Mun, B. Liu, T. H. A. Pham, Q. Wu
    Osteoporosis International.2021; 32(3): 425.     CrossRef
  • 11. No Interaction Effect between Interleukin-6 Polymorphisms and Acid Ash Diet with Bone Resorption Marker in Postmenopausal Women
    Sook Yee Lim, Yoke Mun Chan, Vasudevan Ramachandran, Zalilah Mohd Shariff, Yit Siew Chin, Manohar Arumugam
    International Journal of Environmental Research and Public Health.2021; 18(2): 827.     CrossRef
  • 12. The Effect of Inflammation on Bone
    Scott Epsley, Samuel Tadros, Alexander Farid, Daniel Kargilis, Sameer Mehta, Chamith S. Rajapakse
    Frontiers in Physiology.2021;[Epub]     CrossRef
  • 13. Impact of heart failure severity on bone mineral density among older patients with heart failure
    Yuji Kono, Hideo Izawa, Yoichiro Aoyagi, Ryo Yamada, Tomoya Ishiguro, Masataka Yoshinaga, Satoshi Okumura, Wakaya Fujiwara, Mutsuharu Hayashi, Yohei Otaka
    Heart and Vessels.2021; 36(12): 1856.     CrossRef
  • 14. Sex differences in the longitudinal associations between body composition and bone stiffness index in European children and adolescents
    Lan Cheng, Hermann Pohlabeln, Wolfgang Ahrens, Paola Russo, Toomas Veidebaum, Charalambos Chadjigeorgiou, Dénes Molnár, Gabriele Eiben, Stefaan De Henauw, Luis Moreno, Angie Page, Antje Hebestreit
    Bone.2020; 131: 115162.     CrossRef
  • 15. Potential Role of L-Arginine and Vitamin E Against Bone Loss Induced by Nano-Zinc Oxide in Rats
    Hala M. Abdelkarem, Laila H. Fadda, Eman M. El-Sayed, Omyma K. Radwan
    Journal of Dietary Supplements.2018; 15(3): 300.     CrossRef
  • 16. Are cytokines (IL-6, CRP and adiponectin) associated with bone mineral density in a young adult birth cohort?
    Ana Maria Baptista Menezes, Paula Duarte Oliveira, Helen Gonçalves, Isabel O. Oliveira, Maria Cecilia F. Assunção, Luciana Tovo-Rodrigues, Gustavo Dias Ferreira, Fernando César Wehrmeister
    BMC Musculoskeletal Disorders.2018;[Epub]     CrossRef
  • 17. Relationships between markers of inflammation and bone density: findings from the Hertfordshire Cohort Study
    N. R. Fuggle, L. D. Westbury, H. E. Syddall, N. A. Duggal, S. C. Shaw, K. Maslin, E. M. Dennison, J. Lord, C. Cooper
    Osteoporosis International.2018; 29(7): 1581.     CrossRef
  • 18. Comparison between inflammation-related markers in peri-implant crevicular fluid and clinical parameters during osseointegration in edentulous jaws
    Amália M Bielemann, Raissa M Marcello-Machado, Fábio Renato Manzolli Leite, Frederico Canato Martinho, Otacílio Luiz Chagas-Júnior, Altair Antoninha Del Bel Cury, Fernanda Faot
    Clinical Oral Investigations.2018; 22(1): 531.     CrossRef
  • 19. Association between Plasma Pentraxin 3 Levels and Bone Mineral Density in Elderly Koreans: the Dong-gu Study
    Ran Lee, Hye-Ran Ahn, Min-Ho Shin, Hee-Nam Kim, Young-Hoon Lee, Seong-Woo Choi, Sun-Seog Kweon
    Journal of Korean Medical Science.2018;[Epub]     CrossRef
  • 20. Fexaramine Inhibits Receptor Activator of Nuclear Factor-κB Ligand-induced Osteoclast Formation via Nuclear Factor of Activated T Cells Signaling Pathways
    Ting Zheng, Na-Young Kim, Mijung Yim
    Journal of Bone Metabolism.2017; 24(4): 207.     CrossRef
  • 21. Inflammation and bone mineral density: A Mendelian randomization study
    Jian V. Huang, C. Mary Schooling
    Scientific Reports.2017;[Epub]     CrossRef
  • 22. Analysis of Bone Mineral Density according to Hemoglobin in University Students
    Joon Yoon, Dai-Joong Kim, Hyun-Ho Sung, Yoon-Kyung Jo
    The Korean Journal of Clinical Laboratory Science.2016; 48(4): 296.     CrossRef
  • 4,610 View
  • 19 Download
  • Crossref
Comparison of Calcium Intake Status by Region and Socioeconomic Status in Korea: The 2011-2013 Korea National Health and Nutrition Examination Survey
Hee-Sook Lim, Yoon-Hyung Park, Hae-Hyeog Lee, Tae-Hee Kim, Soon-Kyung Kim
J Bone Metab 2015;22(3):119-126.
Published online August 31, 2015
DOI: https://doi.org/10.11005/jbm.2015.22.3.119
Background

Calcium is an essential element nutrient in our body, and insufficient calcium intake is very common in Korean. Socioeconomic status (SES) is known to be associated with quality of diet and health. The purpose of this study was to compare between calcium intake by region and SES.

Methods

This study used data from a nationally represented sample of Koreans (n=19,249) from 2011 to 2013 Korea National Health and Nutrition Examination Survey. We were divided into six regions: Seoul and Gyeonggi-do, Gangwon-do, Chungcheong-do, Jeolla-do, Gyeongsang-do, and Jeju-do. Daily calcium intake and dietary quality based on 24 hr recall data was calculated and analyzed by the sex, age, SES.

Results

The regions with the highest calcium intakes in both males and females were Seoul and Gyeonggi-do. The age groups with a significant difference in calcium intake, nutrient adequacy ratio, and nutrient density by region were 14 to 19, 20 to 29, and ≥65 years. Calcium intake and dietary quality were lowest in the low household income group. In terms of being a recipient of the dietary life supply, the calcium intake and dietary quality of the recipient group was low.

Conclusions

We found that daily calcium intake was very different by region and was significantly lower in region with lower SES. The findings of this study suggest social inequalities in calcium intake by region can be addressed in the development and implementation of tailored nutritional interventions to promote calcium nutritional status of Koreans.

Citations

Citations to this article as recorded by  Crossref logo
  • 1. The relationship among socioeconomic status, social support and frailty: is there a gender difference?
    Ping Dong, Xian-qi Zhang, Wen-qiang Yin, Zi-yuan Li, Xiao-na Li, Min Gao, Yong-li Shi, Hong-wei Guo, Zhong-ming Chen
    Aging Clinical and Experimental Research.2025;[Epub]     CrossRef
  • 2. Dietary Calcium Intake in Schoolchildren: a Two-Center Observational Study
    Ksenia Yu. Belova, Olga B. Ershova, Irina V. Marusina, Anastasia A. Marusina, Zulfia A. Matyakubova, Anna V. Nazarova, Lidia I. Mozzhukhina, Galina S. Maskova
    Russian Family Doctor.2025; 29(2): 23.     CrossRef
  • 3. Analytical insights on identification and characterization of potential bioactive compounds from two renal lithiasis-resistant plants viz. Aerva lanata and Aerva javanica
    Ravichandran Sanjai, Arun Manomey Rahul, Pinki Kumari Singh, Munusamy Thirumavalavan, Devadasan Velmurugan, Raman Pachaiappan
    Microchemical Journal.2025; 217: 114967.     CrossRef
  • 4. BMI, socioeconomic status, and bone mineral density in U.S. adults: Mediation analysis in the NHANES
    Yun Zhang, Caixia Tan, Wenfu Tan
    Frontiers in Nutrition.2023;[Epub]     CrossRef
  • 5. Effects of Socioeconomic Status on Nutrition and Nutrition Policy Studies in Asia
    Nobuko MURAYAMA
    Journal of Nutritional Science and Vitaminology.2022; 68(Supplement): S92.     CrossRef
  • 6. Is It What They Eat or How Much They Eat That Matters More in Adults with Food Insecurity in a Wealthy-Country Context?
    Min Gyeong Kang, Sung-Min Yook, Ji-Yun Hwang
    Nutrients.2021; 13(3): 851.     CrossRef
  • 7. A Higher Ratio of Serum Calcium to Magnesium Is Associated With Aggressive Clinicopathological Characteristics in the Patients Who Underwent Radical Prostatectomy
    Sang Won Kim, You Jin Lee, Jae-Wook Chung, Yun-Sok Ha, Seock Hwan Choi, Jun Nyung Lee, Bum Soo Kim, Hyun Tae Kim, Tae-Hwan Kim, Eun Sang Yoo, Tae Gyun Kwon
    The Korean Journal of Urological Oncology.2018; 16(1): 25.     CrossRef
  • 8. Low calcium intakes among Australian adolescents and young adults are associated with higher consumption of discretionary foods and beverages
    Anika Saiyara Rouf, Zhixian Sui, Anna Rangan, Amanda Grech, Margaret Allman-Farinelli
    Nutrition.2018; 55-56: 146.     CrossRef
  • 9. Current status and trends in estimated intakes and major food groups of vitamin E among Korean adults: Using the 1~6thKorea National Health and Nutrition Examination Survey
    Seoeun Ahn, Shinyoung Jun, Seong-Ah Kim, Kyungho Ha, Hyojee Joung
    Journal of Nutrition and Health.2017; 50(5): 483.     CrossRef
  • 10. Inadequate dietary intake of minerals: prevalence and association with socio-demographic and lifestyle factors
    Cristiane H. Sales, Mariane de M. Fontanelli, Diva A. S. Vieira, Dirce M. Marchioni, Regina M. Fisberg
    British Journal of Nutrition.2017; 117(2): 267.     CrossRef
  • 11. Comparison in Adherence to Osteoporosis Guidelines according to Bone Health Status in Korean Adult
    Hee-Sook Lim, Soon-Kyung Kim, Hae-Hyeog Lee, Dong Won Byun, Yoon-Hyung Park, Tae-Hee Kim
    Journal of Bone Metabolism.2016; 23(3): 143.     CrossRef
  • 4,638 View
  • 18 Download
  • Crossref